Metal nanoparticles as a potential technique for the diagnosis and treatment of gastrointestinal cancer: a comprehensive review

M Roshani, A Rezaian-Isfahni, MH Lotfalizadeh… - Cancer Cell …, 2023 - Springer
Gastrointestinal (GI) cancer is a major health problem worldwide, and current diagnostic and
therapeutic approaches are often inadequate. Various metallic nanoparticles (MNPs) have …

Raptinal: a powerful tool for rapid induction of apoptotic cell death

AJ Smith, PJ Hergenrother - Cell Death Discovery, 2024 - nature.com
Chemical inducers of apoptosis have been utilized for decades as tools to uncover steps of
the apoptotic cascade and to treat various diseases, most notably cancer. While there are …

Automated detection of apoptotic versus nonapoptotic cell death using label‐free computational microscopy

MA Kabir, A Kharel, S Malla, ZJ Kreis… - Journal of …, 2022 - Wiley Online Library
Identification of cell death mechanisms, particularly distinguishing between apoptotic versus
nonapoptotic pathways, is of paramount importance for a wide range of applications related …

The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity

JP Santavanond, YH Chiu, R Tixeira, Z Liu… - Cell Death & …, 2024 - nature.com
Discovery of new small molecules that can activate distinct programmed cell death pathway
is of significant interest as a research tool and for the development of novel therapeutics for …

[PDF][PDF] Strategies of cell signaling and critical focus on etiology of hepatocellular carcinoma

M Habeeb, A Sugumaran - Biointerface Research in …, 2022 - biointerfaceresearch.com
Hepatocellular carcinoma is an atypical biological cell process that is frequently identified at
an advanced stage, with no promising therapeutic options available. Hepatocarcinogenesis …

Tropaeolum majus L. and low dose gamma radiation suppress liver carcinoma development via EGFR-HER2 signaling pathway

AI Owis, NH Sherif, AA Hassan… - Natural Product …, 2023 - Taylor & Francis
Hepatocellular carcinoma (HCC) is one of the most fatal cancers around the world and
remain asymptomatic in early stage. An alcoholic extract prepared from leaves of …

Nano-Based Drug Delivery Systems in Hepatocellular Carcinoma

MS Abtahi, A Fotouhi, N Rezaei, H Akalin… - Journal of Drug …, 2024 - Taylor & Francis
The high recurrence rate of hepatocellular carcinoma (HCC) and poor prognosis after
medical treatment reflects the necessity to improve the current chemotherapy protocols …

Raptinal ameliorates 1, 2-dimethylhydrazine-induced colon cancer through p53/Bcl2/Bax/caspase-3-mediated apoptotic events in vitro and in vivo

Y Lan, Y Yang, A Das, B Bhattacharya… - Indian Journal of …, 2023 - journals.lww.com
OBJECTIVES: Colon carcinoma stands as the most familiar malignancy throughout across
the globe. Raptinal induce apoptosis through the alteration of cellular events. Thus, in the …

Therapeutic Potential of Aloe vera and Aloe vera–Conjugated Silver Nanoparticles on Mice Exposed to Hexavalent Chromium

T Nauroze, S Ali, S Andleeb, C Ara, I Liaqat… - … Trace Element Research, 2024 - Springer
Abstract Hexavalent chromium (Cr (VI)) is a hazardous heavy metal that induces
hepatotoxicity and nephrotoxicity. Thus, this study was planned to explore the ameliorating …

The DEN and CCl4‐Induced Mouse Model of Fibrosis and Inflammation‐Associated Hepatocellular Carcinoma

T Uehara, IP Pogribny, I Rusyn - Current protocols, 2021 - Wiley Online Library
Human hepatocellular carcinoma (HCC) develops most often as a complication of fibrosis or
cirrhosis. Although most human studies of HCC provide crucial insights into the molecular …