Frailty—A promising concept to evaluate disease vulnerability

AR Ribeiro, SE Howlett, A Fernandes - Mechanisms of Ageing and …, 2020 - Elsevier
With the emergence of diseases, people become frailer and are expected to be less tolerant
of adverse outcomes. Frailty was first described to explain the variability in life expectancy in …

Nutrition interventions for healthy ageing across the lifespan: a conference report

A Kalache, AI De Hoogh, SE Howlett… - European journal of …, 2019 - Springer
Thanks to advances in modern medicine over the past century, the world's population has
experienced a marked increase in longevity. However, disparities exist that lead to groups …

Identifying and implementing endpoints for geriatric mice

LA Toth - Comparative Medicine, 2018 - ingentaconnect.com
The types of changes in physical appearance and behavior that occur in elderly people
similarly develop in elderly animals. Signs and symptoms that might cause concern in …

CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline

F Evans, D Alí-Ruiz, N Rego, ML Negro-Demontel… - Cell reports, 2023 - cell.com
Emerging evidence suggests that immune receptors may participate in many aging-related
processes such as energy metabolism, inflammation, and cognitive decline. CD300f, a …

When will my mouse die? Life span prediction based on immune function, redox and behavioural parameters in female mice at the adult age

IM de Toda, C Vida, LS San Miguel… - Mechanisms of Ageing …, 2019 - Elsevier
The identification of predictive markers of life span would help to unravel the underlying
mechanisms influencing ageing and longevity. For this aim, 30 variables including immune …

Is frailty responsive to surgical correction of adult spinal deformity? An investigation of sagittal re-alignment and frailty component drivers of postoperative frailty status

PG Passias, FA Segreto, KA Moattari, R Lafage… - Spine deformity, 2022 - Springer
Purpose Frailty has been associated with adverse postoperative outcomes. Recently, a
novel frailty index for preoperative risk stratification in patients with adult spinal deformity …

Older HIV-infected adults: complex patients—geriatric syndromes (II)

L Bertagnoli, P Iannuzzi, S Ciccone… - European Geriatric …, 2019 - Springer
With the widespread adoption of highly active antiretroviral therapy (HAART), HIV infection
starts to be considered one of the many chronic illnesses of advanced age. A growing …

Future of aging research

M Cesari, M Canevelli, MU Pérez-Zepeda - Aging Research …, 2018 - Springer
The world population is aging, and this phenomenon is expected to continue for the next
decades. The demographic modifications are substantially altering the socio-economic …

[引用][C] CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline

F Evans Isola, D Alí Ruiz, N Rego… - Cell Reports, 2023, 42 …, 2023 - Cell Press