Molecular mechanisms of viral oncogenesis in humans
NA Krump, J You - Nature Reviews Microbiology, 2018 - nature.com
Viral infection is a major contributor to the global cancer burden. Recent advances have
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …
The MHC class I antigen presentation pathway: strategies for viral immune evasion
EW Hewitt - Immunology, 2003 - Wiley Online Library
Presumably because of the selective pressure exerted by the immune system, many viruses
have evolved proteins that interfere with antigen presentation by major histocompatibility …
have evolved proteins that interfere with antigen presentation by major histocompatibility …
A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics
R Yonashiro, S Ishido, S Kyo, T Fukuda, E Goto… - The EMBO …, 2006 - embopress.org
In this study, we have identified a novel mito chondrial ubiquitin l igase, designated MITOL,
which is localized in the mitochondrial outer membrane. MITOL possesses a Plant Homeo …
which is localized in the mitochondrial outer membrane. MITOL possesses a Plant Homeo …
Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) epidemiology and pathogenesis
LA Dourmishev, AL Dourmishev… - Microbiology and …, 2003 - Am Soc Microbiol
Kaposi's sarcoma had been recognized as unique human cancer for a century before it
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …
Concurrent expression of latent and a limited number of lytic genes with immune modulation and antiapoptotic function by Kaposi's sarcoma-associated herpesvirus …
HH Krishnan, PP Naranatt, MS Smith, L Zeng… - Journal of …, 2004 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) infection of in vitro target cells is
characterized by the expression of the latency-associated open reading frame (ORF) 73 …
characterized by the expression of the latency-associated open reading frame (ORF) 73 …
Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas
I Haecker, LA Gay, Y Yang, J Hu, AM Morse… - 2012 - journals.plos.org
KSHV is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL),
and a subset of multicentricCastleman's disease (MCD). The fact that KSHV-encoded …
and a subset of multicentricCastleman's disease (MCD). The fact that KSHV-encoded …
Quantitative membrane proteomics reveals new cellular targets of viral immune modulators
E Bartee, A McCormack, K Früh - PLoS pathogens, 2006 - journals.plos.org
Immunomodulators of pathogens frequently affect multiple cellular targets, thus preventing
recognition by different immune cells. For instance, the K5 modulator of immune recognition …
recognition by different immune cells. For instance, the K5 modulator of immune recognition …
[HTML][HTML] Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic double-stranded DNA
virus and the etiologic agent of Kaposi's sarcoma and hyperinflammatory lymphoproliferative …
virus and the etiologic agent of Kaposi's sarcoma and hyperinflammatory lymphoproliferative …
Kaposi's sarcoma–associated herpesvirus immunoevasion and tumorigenesis: two sides of the same coin?
▪ Abstract Kaposi's sarcoma–associated herpesvirus (KSHV)[or human herpesvirus 8 (HHV-
8)] is the most frequent cause of malignancy among AIDS patients. KSHV and related …
8)] is the most frequent cause of malignancy among AIDS patients. KSHV and related …
ERK1/2 and MEK1/2 induced by Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) early during infection of target cells are essential for expression of …
N Sharma-Walia, HH Krishnan, PP Naranatt… - Journal of …, 2005 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) in vitro target cell infection is
characterized by the expression of the latency-associated genes ORF 73 (LANA-1), ORF 72 …
characterized by the expression of the latency-associated genes ORF 73 (LANA-1), ORF 72 …