The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Tackling COVID-19 with neutralizing monoclonal antibodies

D Corti, LA Purcell, G Snell, D Veesler - Cell, 2021 - cell.com
Monoclonal antibodies (mAbs) have revolutionized the treatment of several human
diseases, including cancer and autoimmunity and inflammatory conditions, and represent a …

Outbreak. info genomic reports: scalable and dynamic surveillance of SARS-CoV-2 variants and mutations

K Gangavarapu, AA Latif, JL Mullen, M Alkuzweny… - Nature …, 2023 - nature.com
In response to the emergence of SARS-CoV-2 variants of concern, the global scientific
community, through unprecedented effort, has sequenced and shared over 11 million …

Genomics and epidemiology of the P. 1 SARS-CoV-2 lineage in Manaus, Brazil

NR Faria, TA Mellan, C Whittaker, IM Claro… - Science, 2021 - science.org
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …

COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P. 1 emergence

FG Naveca, V Nascimento, VC de Souza, AL Corado… - Nature medicine, 2021 - nature.com
The northern state of Amazonas is among the regions in Brazil most heavily affected by the
COVID-19 epidemic and has experienced two exponentially growing waves, in early and …

Sensitivity of infectious SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants to neutralizing antibodies

D Planas, T Bruel, L Grzelak, F Guivel-Benhassine… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B. 1.1. 7 and B. 1.351
variants were first identified in the United Kingdom and South Africa, respectively, and have …

Resurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence

EC Sabino, LF Buss, MPS Carvalho, CA Prete… - The Lancet, 2021 - thelancet.com
Resurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence - The Lancet Skip to
Main Content Advertisement The Lancet Journal This Journal Back Journal Home Online First …

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant

X Deng, MA Garcia-Knight, MM Khalid, V Servellita… - Cell, 2021 - cell.com
We identified an emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples …

[HTML][HTML] Novel SARS-CoV-2 variants: the pandemics within the pandemic

E Boehm, I Kronig, RA Neher, I Eckerle, P Vetter… - Clinical Microbiology …, 2021 - Elsevier
Background Many new variants of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been termed variants of concern/interest (VOC/I) because of the greater …

Spatiotemporal pattern of COVID-19 spread in Brazil

MC Castro, S Kim, L Barberia, AF Ribeiro, S Gurzenda… - Science, 2021 - science.org
Brazil has been severely hit by COVID-19, with rapid spatial spread of both cases and
deaths. We used daily data on reported cases and deaths to understand, measure, and …