The Wnt/β-catenin signaling pathway exerts integral roles in embryogenesis and adult
homeostasis. Aberrant activation of the pathway is implicated in growth-associated diseases …

One of the significant hallmarks of cancer is angiogenesis. It has a crucial function in tumor
development and metastasis. Thus, angiogenesis has become one of the most exciting …

Lipocalin 2 is a siderophore‐binding protein that regulates iron homeostasis. Lipocalin 2
expression is elevated in multiple tumor types; however, the mechanisms that drive tumor …

Circular RNAs (circRNA), a subclass of noncoding RNA characterized by covalently closed
continuous loops, play emerging roles in tumorigenesis and aggressiveness. However, the …

Abstract Cancer-associated fibroblasts (CAFs), a dominant component of the pancreatic
tumor microenvironment, are mainly considered as promotors of malignant progression, but …

Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress
has been made in recent years, CRC survival remains unsatisfactory due to high metastasis …

Studies over the past four decades have elucidated the role of Wnt/β-catenin mediated
regulation in cell proliferation, differentiation and migration. These processes are …

Wnt/β-catenin-mediated signaling is a key pathway regulating tissue growth and
development, and tumorigenesis, and has received increasing attention in recent years. In …

The beneficial effects of tea consumption on cancer prevention have been generally
reported, while (−)-Epigallocatechin-3-gallate (EGCG) is the major active component from …

Upregulation of special AT-rich sequence-binding protein-1 (SATB1) has been suggested to
promote tumor growth and metastasis. However, the factors governing its cellular levels …