Self-assembling nucleic acid nanostructures functionalized with aptamers

A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Aptamers in biomedicine: Selection strategies and recent advances

G Ștefan, O Hosu, K De Wael, MJ Lobo-Castañón… - Electrochimica …, 2021 - Elsevier
Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the
field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics …

DNA origami nanostructures for controlled therapeutic drug delivery

J Weiden, MMC Bastings - Current Opinion in Colloid & Interface Science, 2021 - Elsevier
DNA nanostructures are emerging as a versatile platform for controlled drug delivery as a
result of recent progress in production yield and strategies to obtain prolonged stability in …

Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales

Y Zhou, J Dong, Q Wang - NPG Asia Materials, 2023 - nature.com
DNA origami technology enables the precise assembly of well-defined two-dimensional and
three-dimensional nanostructures with DNA, an inherently biocompatible material. Given …

Enhanced functional properties of three DNA origami nanostructures as doxorubicin carriers to breast cancer cells

A Udomprasert, C Wootthichairangsan… - ACS Applied Bio …, 2022 - ACS Publications
Previous studies have shown that chemotherapeutic efficacy could be enhanced with
targeted drug delivery. Various DNA origami nanostructures have been investigated as drug …

Synthesis and characterization of biodegradable and antioxidant phosphazene-tannic acid nanospheres and their utilization as drug carrier material

A Onder, H Ozay - Materials Science and Engineering: C, 2021 - Elsevier
In this study, hexachlorocyclotriphosphazene (HCCP) and tannic acid (TA) were used at
different stoichiometric ratios to synthesize cyclomatrix-type polymeric materials with …

Anomalous kinetic study of atenolol release from ATN@ DNA a core-shell like structure

MM Hefny, AS Elmezayyen, AM Tawfik - Scientific Reports, 2023 - nature.com
The need for more efficient drug delivery strategies with ultraprecision and control over the
release of drugs has led to the growth of more sophisticated drug-releasing systems as a …

Advancements in Aptamer‐Driven DNA Nanostructures for Precision Drug Delivery

M Safarkhani, S Ahmadi, H Ipakchi, MR Saeb… - Advanced …, 2024 - Wiley Online Library
DNA nanostructures exhibit versatile geometries and possess sophisticated capabilities not
found in other nanomaterials. They serve as customizable nanoplatforms for orchestrating …

Doxorubicin-loaded DNA origami nanostructures: stability in vitreous and their uptake and toxicity in ocular cells

A Klose, Z Gounani, H Ijäs, T Lajunen, V Linko… - Nanoscale, 2024 - pubs.rsc.org
Biocompatibility and precise control over their size and shape make DNA origami
nanostructures (DONs) promising for drug delivery applications. Whilst many investigations …

Novel electro self-assembled DNA nanospheres as a drug delivery system for atenolol

R Elkayal, A Motawea, FM Reicha… - …, 2021 - iopscience.iop.org
We describe new method for preparing DNA nanospheres for a self-assembled atenolol@
DNA (core/shell) drug delivery system. In this paper, we propose the electrochemical …