Thiamin diphosphate‐dependent enzymes: from enzymology to metabolic regulation, drug design and disease models

VI Bunik, A Tylicki, NV Lukashev - The FEBS journal, 2013 - Wiley Online Library
Bringing a knowledge of enzymology into research in vivo and in situ is of great importance
in understanding systems biology and metabolic regulation. The central metabolic …

Squaramides: bridging from molecular recognition to bifunctional organocatalysis

J Alemán, A Parra, H Jiang… - Chemistry–A European …, 2011 - Wiley Online Library
In this minireview, squaramides are presented from their roots as artificial anion receptors in
molecular recognition studies to their recent advances as powerful bifunctional hydrogen …

Enantioselective Synthesis of Dihydropyrans. Catalysis of Hetero Diels− Alder Reactions by Bis (oxazoline) Copper (II) Complexes

DA Evans, JS Johnson, EJ Olhava - Journal of the American …, 2000 - ACS Publications
C 2-symmetric bis (oxazoline)− Cu (II) complexes 1 and 2 catalyze the inverse electron
demand hetero Diels− Alder reaction of α, β-unsaturated carbonyl compounds (heterodiene) …

[图书][B] Handbook of organophosphorus chemistry

R Engel - 1992 - taylorfrancis.com
This practical work summarizes the development of organophosphorus chemistry in topical
areas and details the discipline's current state-providing applications and experimental …

[图书][B] Modern phosphonate chemistry

P Savignac, B Iorga - 2003 - taylorfrancis.com
A century after their discovery, phosphonates have become important compounds
recognized both for their use as efficient reagents in organic synthesis and for their …

[HTML][HTML] Integrase inhibitor prodrugs: Approaches to enhancing the anti-HIV activity of β-diketo acids

V Nair, M Okello - Molecules, 2015 - mdpi.com
HIV integrase, encoded at the 3′-end of the HIV pol gene, is essential for HIV replication.
This enzyme catalyzes the incorporation of HIV DNA into human DNA, which represents the …

Arginine-and lysine-specific polymers for protein recognition and immobilization

C Renner, J Piehler, T Schrader - Journal of the American …, 2006 - ACS Publications
Free radical polymerization of methacrylamide-based bisphosphonates turns weak arginine
binders into powerful polymeric protein receptors. Dansyl-labeled homo-and copolymers …

[HTML][HTML] 1-Deoxy-D-xylulose 5-phosphate synthase catalyzes a novel random sequential mechanism

LA Brammer, JM Smith, H Wade, CF Meyers - Journal of Biological …, 2011 - ASBMB
Emerging resistance of human pathogens to anti-infective agents make it necessary to
develop new agents to treat infection. The methylerythritol phosphate pathway has been …

[HTML][HTML] Mitochondrial impairment may increase cellular NAD (P) H: resazurin oxidoreductase activity, perturbing the NAD (P) H-based viability assays

VA Aleshin, AV Artiukhov, H Oppermann… - Cells, 2015 - mdpi.com
Cellular NAD (P) H-dependent oxidoreductase activity with artificial dyes (NAD (P) H-OR) is
an indicator of viability, as the cellular redox state is important for biosynthesis and …

Asymmetric conjugate addition of silyl enol ethers catalyzed by tethered bis (8-quinolinolato) aluminum complexes

N Takenaka, JP Abell, H Yamamoto - Journal of the American …, 2007 - ACS Publications
New chiral tethered bis (8-quinolinolato)(TBOx) aluminum (III) complexes effectively catalyze
the highly enantioselective Mukaiyama− Michael reaction of silyl enol ethers, including …