During natural tissue regeneration, tissue microenvironment and stem cell niche including
cell–cell interaction, soluble factors, and extracellular matrix (ECM) provide a train of …

The complex tissue‐specific physiology that is orchestrated from the nano‐to the
macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying …

Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …

Cardiovascular diseases are the leading cause of death worldwide. Therefore, the discovery
of induced pluripotent stem cells (iPSCs) and the subsequent generation of human induced …

Myocardial infarction (MI) is still the leading cause of mortality worldwide. The success of cell-
based therapies and tissue engineering strategies for treatment of injured myocardium have …

Bottom‐up tissue engineering is a promising approach for designing modular biomimetic
structures that aim to recapitulate the intricate hierarchy and biofunctionality of native human …

Myocardial infarction (MI) is one of the fatal diseases in humans. Its incidence is constantly
increasing annually all over the world. The problem is accompanied by the limited …

Owing to their self‐renewal and differentiation ability, stem cells are conducive for repairing
injured tissues, making them a promising source of seed cells for tissue engineering. The …