Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

Microplastics (MPs) have been well demonstrated as potential threats to the ecosystem,
whereas the neurotoxicity of MPs in mammals remains to be elucidated. The current study …

Therapies directed toward the central nervous system remain difficult to translate into
improved clinical outcomes. This is largely due to the blood–brain barrier (BBB), arguably …

In recent years, the researchers and drug designers have given growing attention to new
nanotechnology strategies to improve drug delivery to the central nervous system (CNS) …

Surface modification and endothelialization of vascular biomaterials are common
approaches that are used to both resist the nonspecific adhesion of proteins and improve …

The conventional cancer treatment modalities such as radiotherapy and chemotherapy
suffer from several limitations; hence, their efficiency needs to be improved with other …

Metastasis accounts for the vast majority of cancer deaths. The unique challenges for
treating metastases include their small size, high multiplicity and dispersion to diverse organ …

The blood–brain barrier (BBB) is a highly regulated and efficient barrier that provides a
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …

Nanoparticles enable the delivery of a great variety of drugs including anticancer drugs,
analgesics, anti-Alzheimer's drugs, cardiovascular drugs, protease inhibitors, and several …