Functionalization of diazines and benzo derivatives through deprotonated intermediates

F Chevallier, F Mongin - Chemical Society Reviews, 2008 - pubs.rsc.org
This critical review targets as a readership researchers generally oriented toward organic
synthesis and in particular those active in heterocyclic chemistry. Diazines and benzo …

A Strategy for the total synthesis of dragmacidin E. Construction of the core ring system

RJ Huntley, RL Funk - Organic letters, 2006 - ACS Publications
A Strategy for the Total Synthesis of Dragmacidin E. Construction of the Core Ring System |
Organic Letters ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters …

Molecular spoked wheels: synthesis and self‐assembly studies on rigid nanoscale 2D objects

AV Aggarwal, SS Jester, SM Taheri… - … A European Journal, 2013 - Wiley Online Library
We present the efficient synthesis of a new molecular spoked‐wheel structure (MSW‐3).
Two derivatives with diameters of approximately 4 nm have been prepared. By highlighting …

Ortho-selectivity in SNAr substitutions of 2, 4-dihaloaromatic compounds. Reactions with anionic nucleophiles

MD Wendt, AR Kunzer - Tetrahedron Letters, 2010 - Elsevier
The nucleophilic addition of organic anions to aromatic compounds with halogens
positioned both ortho and para to activating groups was studied in a variety of solvents …

Development of a Late-Stage Diversification Strategy for the 4-and 5-Positions of 4, 5, 6-Trisubstituted Indazoles

JS Barber, A Burtea, MR Collins, M Tran-Dubé… - Organic …, 2020 - ACS Publications
Indazoles represent a privileged motif in drug discovery. However, the formation of highly
substituted indazoles can require the execution of lengthy synthetic routes with minimal …

Fluorine containing diazines. Synthesis and properties

DM Volochnyuk, OO Grygorenko… - Fluorine in Heterocyclic …, 2014 - Springer
This review deals with general and significant developments in the area of chemistry of
fluorinated pyrimidine, pyrazine and pyridazine. Diazines bearing fluoro or α-fluoroalkyl …

Metalation of Pyridazine, Cinnoline, and Phthalazine

E Horkel - Metalation of Azines and Diazines, 2013 - Springer
This chapter reviews the metalation of pyridazine, cinnoline, and phthalazine derivatives as
well as the usage of the hereby formed organometallic compounds in subsequent reactions …

Six-membered ring systems: diazines and benzo derivatives

MP Groziak - Progress in heterocyclic chemistry, 2005 - Elsevier
Publisher Summary This chapter describes the approaches of the diazines pyridazine,
pyrimidine, pyrazine, and their benzo derivatives cinnoline, phthalazine, quinazoline …

Development of new selective synthetic methods en route to privileged scaffolds of pharmaceutical relevance

T Santos - 2022 - teses.usp.br
Since the pioneering works of Gilman and Bebb, and Wittig and Furhmann accompanied by
important contributions including Snieckus, directed ortho-metalation reactions (DoM) have …

[图书][B] Development of synthetic approaches towards 2-substituted 3-and 4-fluorothiophene building blocks and their application in liquid crystal synthesis

P Subramanian - 2013 - search.proquest.com
Thiophene-containing liquid crystals (LCs) often exhibit attractive physical characteristics for
use as ferroelectric materials, which offer several advantages for display applications. In …