RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
Extracellular vesicles and their emerging roles as cellular messengers in endocrinology: an endocrine society scientific statement
During the last decade, there has been great interest in elucidating the biological role of
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …
extracellular vesicles (EVs), particularly, their hormone-like role in cell-to-cell …
Small RNA sequencing across diverse biofluids identifies optimal methods for exRNA isolation
Poor reproducibility within and across studies arising from lack of knowledge regarding the
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …
performance of extracellular RNA (exRNA) isolation methods has hindered progress in the …
Mir-30d regulates cardiac remodeling by intracellular and paracrine signaling
Rationale: Previous translational studies implicate plasma extracellular microRNA-30d (miR-
30d) as a biomarker in left ventricular remodeling and clinical outcome in heart failure (HF) …
30d) as a biomarker in left ventricular remodeling and clinical outcome in heart failure (HF) …
Circulating miRNA analysis for cancer diagnostics and therapy
Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …
The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research
S Das, AB Abdel-Mageed, C Adamidi, PD Adelson… - Cell, 2019 - cell.com
The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …
Small RNA-sequencing: approaches and considerations for miRNA analysis
S Benesova, M Kubista, L Valihrach - Diagnostics, 2021 - mdpi.com
MicroRNAs (miRNAs) are a class of small RNA molecules that have an important regulatory
role in multiple physiological and pathological processes. Their disease-specific profiles and …
role in multiple physiological and pathological processes. Their disease-specific profiles and …
Noncoding RNAs in cardiovascular disease: current knowledge, tools and technologies for investigation, and future directions: a scientific statement from the american …
Background: The discovery that much of the non–protein-coding genome is transcribed and
plays a diverse functional role in fundamental cellular processes has led to an explosion in …
plays a diverse functional role in fundamental cellular processes has led to an explosion in …
Biomarkers and lung cancer early detection: state of the art
Simple Summary Lung cancer is the leading cause of cancer death worldwide. Detecting
lung malignancies promptly is essential for any anticancer treatment to reduce mortality and …
lung malignancies promptly is essential for any anticancer treatment to reduce mortality and …
Comparison of reproducibility, accuracy, sensitivity, and specificity of miRNA quantification platforms
PM Godoy, AJ Barczak, P DeHoff, S Srinivasan… - Cell reports, 2019 - cell.com
Given the increasing interest in their use as disease biomarkers, the establishment of
reproducible, accurate, sensitive, and specific platforms for microRNA (miRNA) …
reproducible, accurate, sensitive, and specific platforms for microRNA (miRNA) …