Lubricin is a surface-active mucinous glycoprotein secreted in the synovial joint that plays an
important role in cartilage integrity. In healthy joints, lubricin molecules coat the cartilage …

Osteoarthritis is the most common degenerative and highly prevalent joint disease,
characterized by progressive loss and destruction of articular cartilage. The damaged …

Hydration lubrication has emerged as a new paradigm for lubrication in aqueous and
biological media, accounting especially for the extremely low friction (friction coefficients …

Cartilage is a hydrated biomacromolecular fiber composite located at the ends of long bones
that enables proper joint lubrication, articulation, loading, and energy dissipation …

Synovial fluid is a semidilute hyaluronate (HA) polymer solution, the rheology of which
depends on HA–protein interactions, and lubricin is a HA-binding protein found in synovial …

Objective The glycoprotein lubricin (encoded by the gene Prg4) is secreted by surface
chondrocytes and synovial cells, and has been shown to reduce friction in vitro. In contrast to …

The lubrication of synovial joints is extremely efficient, allowing smooth motion to be
performed between relatively soft and vulnerable cartilage surfaces for close to 100 years. A …

At present, more and more diseases are associated with the lubrication dysfunction, which
requires a systematic study of the complex lubrication behavior of tissues and organs in …

The lubricating behavior of the weakly charged short-side-chain glycoprotein mucin
“Orthana”(M w= 0.55 MDa) has been investigated between hydrophobic and hydrophilic …

As-placed contact angle is the contact angle a drop adapts as a result of its placement on a
surface. As expected, the as-placed contact angle, θAP, of a sessile drop on a horizontal …