Plasmodium falciparum malaria, an infectious disease caused by a parasitic protozoan,
claims the lives of nearly a million children each year in Africa alone and is a top public …

Cerebral malaria is the most severe neurological complication of infection with Plasmodium
falciparum. With> 575,000 cases annually, children in sub-Saharan Africa are the most …

While complex physiological mechanisms exist to regulate and optimize tissue oxygenation
under various conditions, clinical and experimental evidence indicates that anaemia …

Background Neuroinflammatory processes have been hypothesized to play a role in the
pathogenesis of psychiatric and neurological diseases. Studies on this topic often rely on …

OBJECTIVE: The purpose of this study was to evaluate the efficacy and safety of
erythropoietin in neonatal hypoxic-ischemic encephalopathy (HIE), by using a randomized …

In its classic hormonal role, erythropoietin (EPO) is produced by the kidney and regulates
the number of erythrocytes within the circulation to provide adequate tissue oxygenation …

Adherence of parasitized erythrocytes to activated endothelium causes microvascular
obstruction, tissue ischemia, and clinical complications in severe malaria (SM); however, the …

Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Cerebral malaria is a life-threatening complication of malaria infection. The pathogenesis of
cerebral malaria is poorly defined and progress in understanding the condition is severely …

Malaria, the most prevalent mosquito-borne infectious disease worldwide, has accompanied
humanity for millennia and remains an important public health issue despite advances in its …