As a vital component of blood vessels, endothelial cells play a key role in maintaining
overall physiological function by residing between circulating blood and semi-solid tissue …

Kidneys are highly vascular organs that despite their relatively small size receive 20% of the
cardiac output. The highly intricate, delicately organized structure of renal microcirculation is …

Impairment of moment-to-moment adjustment of cerebral blood flow (CBF) via
neurovascular coupling is thought to play a critical role in the genesis of cognitive …

Abstract Charcot-Marie-Tooth 2A (CMT2A) is an inherited peripheral neuropathy caused by
mutations in MFN2, which encodes a mitochondrial membrane protein involved in …

The underlying factors promoting increased mitochondrial proteins, mtDNA, and dilation to
mitochondrial-specific agents in male rats following tMCAO are not fully elucidated. Our goal …

Mitochondria not only produce energy in the form of ATP to support the activities of cells
comprising the neurovascular unit, but mitochondrial events, such as depolarization and/or …

The identification of proteins involved in brain ischemia might allow the discovery of putative
biomarkers or therapeutic targets for ischemic stroke. Our aim is to study the distribution of …

Vascular endothelial cells, serving as a barrier between blood and the arterial wall, play a
crucial role in the early stages of the development of atherosclerosis, cardiovascular …

Mitochondrial numbers and dynamics in brain blood vessels differ between young male and
female rats under physiological conditions, but how these differences are affected by stroke …

The diverse signaling events following mitochondrial depolarization in neurons are not
clear. We examined for the first time the effects of mitochondrial depolarization on …