Understanding the promises and hurdles of metagenomic next-generation sequencing as a diagnostic tool for infectious diseases
PJ Simner, S Miller, KC Carroll - Clinical Infectious Diseases, 2018 - academic.oup.com
Agnostic metagenomic next-generation sequencing (mNGS) has emerged as a promising
single, universal pathogen detection method for infectious disease diagnostics. This …
single, universal pathogen detection method for infectious disease diagnostics. This …
Prediction and prevention of the next pandemic zoonosis
Most pandemics—eg, HIV/AIDS, severe acute respiratory syndrome, pandemic influenza—
originate in animals, are caused by viruses, and are driven to emerge by ecological …
originate in animals, are caused by viruses, and are driven to emerge by ecological …
The global virome project
Outbreaks of novel and deadly viruses highlight global vulnerability to emerging diseases,
with many having massive health and economic impacts. Our adaptive toolkit—based …
with many having massive health and economic impacts. Our adaptive toolkit—based …
Actionable diagnosis of neuroleptospirosis by next-generation sequencing
MR Wilson, SN Naccache, E Samayoa… - … England Journal of …, 2014 - Mass Medical Soc
A 14-year-old boy with severe combined immunodeficiency presented three times to a
medical facility over a period of 4 months with fever and headache that progressed to …
medical facility over a period of 4 months with fever and headache that progressed to …
Arbidol as a broad-spectrum antiviral: an update
J Blaising, SJ Polyak, EI Pécheur - Antiviral research, 2014 - Elsevier
Arbidol (ARB) is a Russian-made small indole-derivative molecule, licensed in Russia and
China for prophylaxis and treatment of influenza and other respiratory viral infections. It also …
China for prophylaxis and treatment of influenza and other respiratory viral infections. It also …
A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012–14): a retrospective cohort study
Background Enterovirus D68 was implicated in a widespread outbreak of severe respiratory
illness across the USA in 2014 and has also been reported sporadically in patients with …
illness across the USA in 2014 and has also been reported sporadically in patients with …
A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples
Unbiased next-generation sequencing (NGS) approaches enable comprehensive pathogen
detection in the clinical microbiology laboratory and have numerous applications for public …
detection in the clinical microbiology laboratory and have numerous applications for public …
Taxonomy of the order Mononegavirales: update 2017
In 2017, the order Mononegavirales was expanded by the inclusion of a total of 69 novel
species. Five new rhabdovirus genera and one new nyamivirus genus were established to …
species. Five new rhabdovirus genera and one new nyamivirus genus were established to …
Next generation sequencing and bioinformatics methodologies for infectious disease research and public health: approaches, applications, and considerations for …
I Maljkovic Berry, MC Melendrez… - The Journal of …, 2020 - academic.oup.com
Next generation sequencing (NGS) combined with bioinformatics has successfully been
used in a vast array of analyses for infectious disease research of public health relevance …
used in a vast array of analyses for infectious disease research of public health relevance …
Modern clinical microbiology: new challenges and solutions
PE Fournier, M Drancourt, P Colson… - Nature Reviews …, 2013 - nature.com
In the twenty-first century, the clinical microbiology laboratory plays a central part in
optimizing the management of infectious diseases and surveying local and global …
optimizing the management of infectious diseases and surveying local and global …