HE4 as a Biomarker for Endometrial Cancer

R Behrouzi, CE Barr, EJ Crosbie - Cancers, 2021 - mdpi.com
Simple Summary There are currently no blood biomarkers approved for routine clinical use
in endometrial cancer. Serum human epididymis protein 4 (HE4) is significantly higher in …

The performance of HE4 alone and in combination with CA125 for the detection of ovarian cancer in an enriched primary care population

CE Barr, G Funston, D Jeevan, S Sundar, LTA Mounce… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer is the most common cause of death from gynaecological
cancer in the UK. Survival is better when the disease is diagnosed early. However …

Protein glycosylation as biomarkers in gynecologic cancers

H Shen, CY Lee, CH Chen - Diagnostics, 2022 - mdpi.com
Gynecologic cancers are the leading cause of death in women. Endometrial, ovarian, and
cervical cancer are the three main types of gynecologic cancers. Poor prognoses and high …

Urine CA125 and HE4 for the detection of ovarian cancer in symptomatic women

CE Barr, K Njoku, GL Owens, EJ Crosbie - Cancers, 2023 - mdpi.com
Simple Summary Early diagnosis of ovarian cancer is challenging due to vague symptoms
and a lack of screening tools. We aimed to evaluate two simple, non-invasive urine …

Urine CA125 and HE4 for the triage of symptomatic women with suspected endometrial cancer

K Njoku, CE Barr, CJJ Sutton, EJ Crosbie - Cancers, 2022 - mdpi.com
Simple Summary Women with suspected endometrial cancer undergo investigations that
can be painful and anxiety-provoking. These tests are avoidable, as only 5–10% of …

Serum CA125 and HE4 as biomarkers for the detection of endometrial cancer and associated high-risk features

CE Barr, K Njoku, ER Jones, EJ Crosbie - Diagnostics, 2022 - mdpi.com
Early detection of endometrial cancer improves survival. Non-invasive diagnostic
biomarkers would improve triage of symptomatic women for investigations. This study aimed …

Comparison of the ADNEX and ROMA risk prediction models for the diagnosis of ovarian cancer: a multicentre external validation in patients who underwent surgery

C Landolfo, J Ceusters, L Valentin, W Froyman… - British Journal of …, 2024 - nature.com
Background Several diagnostic prediction models to help clinicians discriminate between
benign and malignant adnexal masses are available. This study is a head-to-head …

New analytical approach for the alignment of different HE4 automated immunometric systems: An italian multicentric study

A Angeloni, C De Vito, A Farina, D Terracciano… - Journal of Clinical …, 2022 - mdpi.com
Human epididymal secretory protein 4 (HE4) elevation has been studied as a crucial
biomarker for malignant gynecological cancer, such us ovarian cancer (OC). However, there …

Evaluation of the Comparability of Wantai Wan200+ Instrument with Routine Laboratory Assays for 21 Different Analytes

I Talli, A Padoan, C Cosma, G Furlan… - Journal of Clinical …, 2024 - mdpi.com
Background: We compared the performance of 21 different assays performed by the Wantai
Wan200+ (Wantai BioPharm, Beijing, China) with respect to other methods in use at the …

Validation of in vitro-produced and freeze-dried whole cell lysate antigens for ELISA Trypanosoma evansi antibody detection in camels

G Bossard, M Desquesnes - Veterinary Parasitology, 2023 - Elsevier
Trypanosoma evansi is a blood parasite responsible for surra in mammals, with a high
impact in camels and horses. The WOAH-recommended reference method for detecting …