The microbiome, cancer, and cancer therapy

BA Helmink, MAW Khan, A Hermann… - Nature medicine, 2019 - nature.com
With the advent of next-generation sequencing, we have an unprecedented ability to study
tumor and host genomes as well as those of the vast array of microorganisms that exist …

Gut microbiota and cancer: from pathogenesis to therapy

S Vivarelli, R Salemi, S Candido, L Falzone… - Cancers, 2019 - mdpi.com
Cancer is a multifactorial pathology and it represents the second leading cause of death
worldwide. In the recent years, numerous studies highlighted the dual role of the gut …

Gut microbes and muscle function: can probiotics make our muscles stronger?

M Giron, M Thomas, D Dardevet… - Journal of cachexia …, 2022 - Wiley Online Library
Evidence suggests that gut microbiota composition and diversity can be a determinant of
skeletal muscle metabolism and functionality. This is true in catabolic (sarcopenia and …

The gut microbiome: what the oncologist ought to know

KA Lee, MK Luong, H Shaw, P Nathan… - British journal of …, 2021 - nature.com
The gut microbiome (GM) has been implicated in a vast number of human pathologies and
has become a focus of oncology research over the past 5 years. The normal gut microbiota …

Therapeutic bacteria to combat cancer; current advances, challenges, and opportunities

M Sedighi, A Zahedi Bialvaei, MR Hamblin… - Cancer …, 2019 - Wiley Online Library
Successful treatment of cancer remains a challenge, due to the unique pathophysiology of
solid tumors, and the predictable emergence of resistance. Traditional methods for cancer …

Pharmacomicrobiomics: exploiting the drug-microbiota interactions in anticancer therapies

C Panebianco, A Andriulli, V Pazienza - Microbiome, 2018 - Springer
Cancer is a major health burden worldwide, and despite continuous advances in medical
therapies, resistance to standard drugs and adverse effects still represent an important …

Dietary factors modulating colorectal carcinogenesis

F Vernia, S Longo, G Stefanelli, A Viscido, G Latella - Nutrients, 2021 - mdpi.com
The development of colorectal cancer, responsible for 9% of cancer-related deaths, is
favored by a combination of genetic and environmental factors. The modification of diet and …

Microencapsulating alginate-based polymers for probiotics delivery systems and their application

X Wang, S Gao, S Yun, M Zhang, L Peng, Y Li, Y Zhou - Pharmaceuticals, 2022 - mdpi.com
Probiotics exhibit many health benefits and a great potential for broad applications in
pharmaceutical fields, such as prevention and treatment of gastrointestinal tract diseases …

[HTML][HTML] Role of diet and gut microbiota on colorectal cancer immunomodulation

CV De Almeida, MR de Camargo, E Russo… - World journal of …, 2019 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers, and it is
characterized by genetic and epigenetic alterations, as well as by inflammatory cell …

Chemotherapy-induced intestinal microbiota dysbiosis impairs mucosal homeostasis by modulating toll-like receptor signaling pathways

L Wei, XS Wen, CJ Xian - International journal of molecular sciences, 2021 - mdpi.com
Chemotherapy-induced intestinal mucositis, a painful debilitating condition affecting up to 40–
100% of patients undergoing chemotherapy, can reduce the patients' quality of life, add …