The evolution of regulated cell death pathways in animals and their evasion by pathogens

B Tummers, DR Green - Physiological reviews, 2022 - journals.physiology.org
The coevolution of host-pathogen interactions underlies many human physiological traits
associated with protection from or susceptibility to infections. Among the mechanisms that …

Caspase-8 function, and phosphorylation, in cell migration

N Keller, D Ozmadenci, G Ichim, D Stupack - Seminars in Cell & …, 2018 - Elsevier
Caspase-8 is involved in a number of cellular functions, with the most well established being
the control of cell death. Yet caspase-8 is unique among the caspases in that it acts as an …

[HTML][HTML] Azadirachta indica leaves mediated green synthesized copper oxide nanoparticles induce apoptosis through activation of TNF-α and caspases signaling …

A Dey, S Manna, S Chattopadhyay, D Mondal… - Journal of Saudi …, 2019 - Elsevier
Green nanotechnology elucidates highly prioritized anticancer activity. We synthesized
Copper oxide nanoparticles (CuONPs) using leaves of Azadirachta indica (A. indica) plants …

Rapid acclimation of juvenile corals to CO2‐mediated acidification by upregulation of heat shock protein and Bcl‐2 genes

A Moya, L Huisman, S Foret, JP Gattuso… - Molecular …, 2015 - Wiley Online Library
Corals play a key role in ocean ecosystems and carbonate balance, but their molecular
response to ocean acidification remains unclear. The only previous whole‐transcriptome …

Phylogenetic analysis of the caspase family in bivalves: implications for programmed cell death, immune response and development

S Vogeler, S Carboni, X Li, A Joyce - BMC genomics, 2021 - Springer
Background Apoptosis is an important process for an organism's innate immune system to
respond to pathogens, while also allowing for cell differentiation and other essential life …

Functional conservation of the apoptotic machinery from coral to man: the diverse and complex Bcl-2 and caspase repertoires of Acropora millepora

A Moya, K Sakamaki, BM Mason, L Huisman, S Forêt… - BMC genomics, 2016 - Springer
Background Apoptotic cell death is a defining and ubiquitous characteristic of metazoans,
but its evolutionary origins are unclear. Although Caenorhabditis and Drosophila played key …

Evolutionary analyses of caspase‐8 and its paralogs: deep origins of the apoptotic signaling pathways

K Sakamaki, K Imai, K Tomii, DJ Miller - Bioessays, 2015 - Wiley Online Library
Although Caenorhabditis and Drosophila proved invaluable in unraveling the molecular
mechanisms of apoptosis, it is now clear that these animals are of limited value for …

DED or alive: assembly and regulation of the death effector domain complexes

JS Riley, A Malik, C Holohan, DB Longley - Cell death & disease, 2015 - nature.com
Death effector domains (DEDs) are protein–protein interaction domains initially identified in
proteins such as FADD, FLIP and caspase-8 involved in regulating apoptosis. Subsequently …

The tumor necrosis factor family: family conventions and private idiosyncrasies

D Wallach - Cold Spring Harbor perspectives in biology, 2018 - cshperspectives.cshlp.org
The tumor necrosis factor (TNF) cytokine family and the TNF/nerve growth factor (NGF)
family of their cognate receptors together control numerous immune functions, as well as …

Apoptosis: mediator molecules, interplay with other cell death processes and therapeutic potentials

J Barman, R Kumar, G Saha, K Tiwari… - Current …, 2018 - ingentaconnect.com
Apoptosis, a form of programmed cell death, plays a very crucial role in various
physiological processes for maintaining cell homeostasis. This process has several …