Purinergic signalling, ie, the role of nucleotides as extracellular signalling molecules, was
proposed in 1972. However, this concept was not well accepted until the early 1990's when …

Eight G protein‐coupled P2Y receptor subtypes respond to extracellular adenine and uracil
mononucleotides and dinucleotides. P2Y receptors belong to the δ group of rhodopsin‐like …

Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …

Abstract Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a master regulator of cellular
homeostasis that controls the expression of more than 1% of human genes related to …

This review outlined evidence that purinergic signaling is involved in the modulation of
blood-brain barrier (BBB) permeability. The functional and structural integrity of the BBB is …

Purinergic signalling, ie ATP as an extracellular signalling molecule and cotransmitter in
both peripheral and central neurons, is involved in the physiology of neurotransmission and …

Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups …

The principle functions of neuroinflammation are to limit tissue damage and promote tissue
repair in response to pathogens or injury. While neuroinflammation has utility …

Purinergic receptors play important roles in central nervous system (CNS). These receptors
are involved in cellular neuroinflammatory responses that regulate functions of neurons …

Dual-specificity protein phosphatases comprise a protein phosphatase subfamily with
selectivity towards mitogen-activated protein (MAP) kinases, also named MKPs, or mitogen …