HLA-G is a molecule that was first known to confer protection to the fetus from destruction by
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …

In human tumors alterations in the surface expression and/or function of the major
histocompatibility complex (MHC) class I antigens are frequently found and equip neoplastic …

Background HLA-G is an immune checkpoint molecule. Since a differential molecule
expression has been reported even for healthy individuals, many studies have focused on …

Human leukocyte antigen-G (HLA-G) is known to be implicated in a tumor-driven immune
escape mechanism in malignancies. The purpose of this study was to investigate HLA-G …

The human leukocyte antigen‐G (HLA‐G) is considered an immune checkpoint molecule
involved in tumor immune evasion. Hypoxia and the metabolic sensor hypoxia‐inducible …

The immunotolerant human leukocyte antigen (HLA)-G has direct inhibitory effects on
natural killer cells, dendritic cells, T cells and can indirectly induce tolerant regulatory cells …

Human leukocyte antigen (HLA)-G, a non-classical HLA-class I molecule, has a low
polymorphism frequency, restricted tissue distribution and immunoinhibitory property. HLA-G …

As a non-classic major histocompatibility complex (MHC) class I molecule, human leukocyte
antigen G (HLA-G) is expressed in fetal-maternal interface and immunoprivileged site only in …

Gynaecological tumours that threaten the health of women, especially when advanced and
recurrent, have remained mostly intractable to existing treatments. Therefore, new …

Besides HPV infection, the progression to cervical cancer also depends on the host immune
response. HLA-G molecules are involved in the inhibition of cell-mediated immune …