Background The introduction of proton pump inhibitors (PPIs) into clinical practice has
revolutionized the management of acid-related diseases. Studies in primary care and …

As an increase in gastroesophageal reflux disease (GERD) has been reported in Japan,
and public interest in GERD has been increasing, the Japanese Society of Gastroenterology …

OBJECTIVES A globally acceptable definition and classification of gastroesophageal reflux
disease (GERD) is desirable for research and clinical practice. The aim of this initiative was …

Objective: To develop a North American Society for Pediatric Gastroenterology, Hepatology,
and Nutrition (NASPGHAN) and European Society for Pediatric Gastroenterology …

SUMMARY A systematic review of the epidemiology of gastro-oesophageal reflux disease
(GORD) has been performed, applying strict criteria for quality of studies and the disease …

Background Gastroesophageal reflux disease (GERD) is one of the most frequent benign
disorders of the upper gastrointestinal tract. Management of GERD has always been …

OBJECTIVES: We sought to develop an international consensus on the definition of
gastroesophageal reflux disease (GERD) in the pediatric population. METHODS: Using the …

Background Recently, it has been suggested that low esophageal basal impedance may
reflect impaired mucosal integrity and increased acid sensitivity. We aimed to compare …

This literature review and the recommendations therein were prepared for the American
Gastroenterological Association Clinical Practice and Economics Committee. The paper was …

Objective. Gastroesophageal reflux disease has been reported to be a common burden on
health-care resources in the Western world, but its manifestations in the general population …