Analytical research with adverse environmental impact has caused a severe rise in concern
about the ecological consequences of its strategies, most notably the use and emission of …

Voriconazole, a second-generation triazole frequently used for the prophylaxis and
treatment of invasive fungal infections, undergoes complex metabolism mainly involving …

Abstract Background and Objective Voriconazole (VRC), a broad-spectrum antifungal drug,
exhibits nonlinear pharmacokinetics (PK) due to saturable metabolic processes …

Systematic review of literature coupled with integrative research of published data for
triazole antifungal agents was done. The investigated literature covered chromatographic …

We have developed and validated a high-performance liquid chromatography method
coupled with a mass detector to quantify itraconazole, voriconazole, and posaconazole …

Voriconazole is a broad spectrum agent used to treat serious fungal infections. Stability
studies conducted so far refer to the stability of the injectable formulation in different …

Method validation is being applied in the reported analytical methods for decades. Even
before this protocol was defined, authors already somehow validated their methods without …

Voriconazole, a broad-spectrum antifungal drug used to prevent and treat invasive fungal
infections, shows complex pharmacokinetics and is primarily metabolised by various CYP …

Voriconazole (VCZ) is a triazolic drug used to treat serious fungal infections and invasive
mycosis and has also been more recently used as a generic antifungal treatment. However …

Voriconazole (VRC) pharmacokinetics, in particular its complex metabolism, is still not fully
understood which challenges its optimal therapeutic use. To increase knowledge on the …