Piperazine ranks as the third most common N-heterocycle appearing in small-molecule
pharmaceuticals. This review highlights recent advances in methods development for the …

Heterogeneous catalysts enabling multiple reaction sequences in one pot have a great
potential for large‐scale production processes in terms of productivity, cost‐effectiveness …

It has been found that a bifunctional metal Pd/base (MgO) catalyst performs the selective
monoalkylation of amines with alcohols. The reaction goes through a series of consecutive …

Chiral allenes are readily accessed in a single pot operation in the reaction of terminal
alkynes, aldehydes, chiral secondary amines, and zinc halides in good yields (up to 77 …

A straightforward procedure is described for the synthesis of piperazines from amines and 1,
2‐diols. The heterocyclization is catalyzed by [Cp* IrCl2] 2 and sodium hydrogen carbonate …

Iridium catalysed synthesis of piperazines from diols - Chemical Communications (RSC
Publishing) DOI:10.1039/B712685A Royal Society of Chemistry View PDF VersionPrevious …

Metal catalysts based on Pt and Pd nano-particles supported on structured microporous
Beta zeolites and mesoporous MCM-41 materials, as well as specially designed γ-Al2O3 …

A highly diastereoselective desymmetrization of p-quinamines via regioselective ring
opening of epoxides and aziridines under mild conditions has been developed. A chairlike …

A convenient and efficient synthetic method for the construction of morpholine and
piperazine derivatives in moderate to good yields was established. The reaction proceeds …

Stereospecific Cu-catalyzed nucleophilic ring opening of N-sulfonylaziridines with
propargylamines and subsequent hydroamination afford piperazines, which leads to double …