The hippocampus is a vulnerable and plastic brain structure that is damaged by a variety of
stimuli, eg hypoxia, hypoperfusion, hypoglycaemia, stress and seizures. Alzheimer's disease …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder which impairs the
memory and intellectual abilities of the affected individuals. Loss of episodic as well as …

Rates of hippocampal volume loss have been shown to distinguish subjects with dementia
of the Alzheimer type (DAT) from nondemented controls (Jack et al., 2000). In this study, we …

We used a new method we developed for automated hippocampal segmentation, called the
auto context model, to analyze brain MRI scans of 400 subjects from the Alzheimer's disease …

BACKGROUND: Although many studies of adults with posttraumatic stress disorder (PTSD)
have reported smaller hippocampal volume compared with control subjects, comparable …

The aim of the present study is to evaluate the diagnostic value of diffusion tensor imaging
(DTI) for early Alzheimer's disease (AD) in comparison to widely accepted medial temporal …

Most previous magnetic resonance imaging (MRI) studies of patients with bipolar disorder
(BD) report similar hippocampus (HC) volumes across patients and controls, but because …

Objectives The efficacy, safety and disease-modification of tramiprosate (homotaurine) were
investigated in a recently completed large-scale Phase III clinical study in patients with mild …

Background Alzheimer's disease (AD) is the most common neurodegenerative disease,
characterized by the deposition of extracellular fibrillar amyloid β (fΑβ) and the intracellular …

OBJECTIVE Hippocampal neurons in adult animals and humans are vulnerable to severe
hypoglycemia and hyperglycemia. Effects are hypothesized to be exacerbated during …