Recent review on selected xenobiotics and their impacts on gut microbiome and metabolome
As it is well known, the gut is one of the primary sites in any host for xenobiotics, and the
many microbial metabolites responsible for the interactions between the gut microbiome and …
many microbial metabolites responsible for the interactions between the gut microbiome and …
Loss of fatty acid degradation by astrocytic mitochondria triggers neuroinflammation and neurodegeneration
Astrocytes provide key neuronal support, and their phenotypic transformation is implicated in
neurodegenerative diseases. Metabolically, astrocytes possess low mitochondrial oxidative …
neurodegenerative diseases. Metabolically, astrocytes possess low mitochondrial oxidative …
[HTML][HTML] Lipid profile in breast cancer: From signaling pathways to treatment strategies
HT Ribas, MC Sogayar, AM Dolga, SMB Winnischofer… - Biochimie, 2024 - Elsevier
Breast cancer is the most prevalent cancer in women. Metabolic abnormalities, particularly
increased lipid synthesis and uptake, impact the onset and progression of the disease …
increased lipid synthesis and uptake, impact the onset and progression of the disease …
Early breast cancer detection using untargeted and targeted metabolomics
Breast cancer (BC) is a common cause of morbidity and mortality, particularly in women.
Moreover, the discovery of diagnostic biomarkers for early BC remains a challenging task …
Moreover, the discovery of diagnostic biomarkers for early BC remains a challenging task …
Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK
Mitochondrial dynamics regulated by mitochondrial fusion and fission maintain
mitochondrial functions, whose alterations underline various human diseases. Here, we …
mitochondrial functions, whose alterations underline various human diseases. Here, we …
Inhibition of glycolysis in the presence of antigen generates suppressive antigen-specific responses and restrains rheumatoid arthritis in mice
Dendritic cells (DCs) rely on glycolysis for their energy needs to induce pro-inflammatory
antigen-specific immune responses. Therefore, inhibiting DC glycolysis, while presenting …
antigen-specific immune responses. Therefore, inhibiting DC glycolysis, while presenting …
Advances in early breast cancer risk profiling: from histopathology to molecular technologies
Simple Summary Risk stratification for early breast cancer (BC) is extremely relevant for
tailoring clinical decisions but challenging due to the absence of comprehensive guidelines …
tailoring clinical decisions but challenging due to the absence of comprehensive guidelines …
Metabolic profiling of neocortical tissue discriminates Alzheimer's disease from mild cognitive impairment, high pathology controls, and normal controls
Alzheimer's disease (AD) is the most common cause of dementia, accounting for an
estimated 60–80% of cases, and is the sixth-leading cause of death in the United States …
estimated 60–80% of cases, and is the sixth-leading cause of death in the United States …
Liquid-based biomarkers in breast cancer: looking beyond the blood
Y Shuai, Z Ma, J Ju, T Wei, S Gao, Y Kang… - Journal of Translational …, 2023 - Springer
In recent decades, using circulating tumor cell (CTC), circulating tumor DNA (ctDNA),
circulating tumor RNA (ctRNA), exosomes and etc. as liquid biomarkers has received …
circulating tumor RNA (ctRNA), exosomes and etc. as liquid biomarkers has received …
Metabolomic signatures of autism spectrum disorder
Autism Spectrum Disorder (ASD) is associated with many variations in metabolism, but the
ex-act correlates of these metabolic disturbances with behavior and development and their …
ex-act correlates of these metabolic disturbances with behavior and development and their …