Many first-line treatments for neglected tropical diseases identified by the World Health
Organization (WHO) are limited by one or more of the following: the development of drug …

The widespread use of antibiotics has resulted in the emergence of drug-resistant
populations of microorganisms. Clearly, one can see the need to develop new, more …

Toxoplasma gondii is an apicomplexan parasite that infects and proliferates within many
different types of host cells and infects virtually all warm-blooded animals and humans …

Leishmaniasis and Chagas disease are still considered neglected illnesses due to the lack
of investment in research, despite the fact that almost one million new cases are reported …

Aiming toward compounds with improved anti-Toxoplasma activity by exploiting the parasite
auxotrophies, a library of nucleobase-tethered trithiolato-bridged dinuclear ruthenium (II) …

Scaffolds of metal-based compounds can act as pharmacophore groups in several ligands
to treat various diseases, including tropical infectious diseases (TID). In this review article …

The coordination of metal ions with flavonoids is applied to improve its pharmacological
properties. To evaluate the role of ions on diosmin new complexes with Fe (II), Cu (II) and Co …