[HTML][HTML] Antibacterial approaches in tissue engineering using metal ions and nanoparticles: From mechanisms to applications

M Godoy-Gallardo, U Eckhard, LM Delgado… - Bioactive Materials, 2021 - Elsevier
Bacterial infection of implanted scaffolds may have fatal consequences and, in combination
with the emergence of multidrug bacterial resistance, the development of advanced …

Oxidative stress, protein damage and repair in bacteria

B Ezraty, A Gennaris, F Barras, JF Collet - Nature Reviews Microbiology, 2017 - nature.com
Oxidative damage can have a devastating effect on the structure and activity of proteins, and
may even lead to cell death. The sulfur-containing amino acids cysteine and methionine are …

Copper tolerance in bacteria requires the activation of multiple accessory pathways

A Giachino, KJ Waldron - Molecular microbiology, 2020 - Wiley Online Library
Copper is a required micronutrient for bacteria and an essential cofactor for redox‐active
cuproenzymes. Yet, excess copper is extremely toxic, and is exploited as a bacteriocide in …

Nitrosopumilus maritimus genome reveals unique mechanisms for nitrification and autotrophy in globally distributed marine crenarchaea

CB Walker, JR de la Torre, MG Klotz… - Proceedings of the …, 2010 - National Acad Sciences
Ammonia-oxidizing archaea are ubiquitous in marine and terrestrial environments and now
thought to be significant contributors to carbon and nitrogen cycling. The isolation of …

Copper tolerance and virulence in bacteria

E Ladomersky, MJ Petris - Metallomics, 2015 - academic.oup.com
Copper (Cu) is an essential trace element for all aerobic organisms. It functions as a cofactor
in enzymes that catalyze a wide variety of redox reactions due to its ability to cycle between …

Copper induces protein aggregation, a toxic process compensated by molecular chaperones

L Zuily, N Lahrach, R Fassler, O Genest, P Faller… - MBio, 2022 - Am Soc Microbiol
Copper is well known for its antimicrobial and antiviral properties. Under aerobic conditions,
copper toxicity relies in part on the production of reactive oxygen species (ROS), especially …

Biochemical pathways of copper complexes: Progress over the past 5 years

S Zehra, S Tabassum, F Arjmand - Drug Discovery Today, 2021 - Elsevier
Highlights•Overview of copper complexes as potent anticancer chemotherapeutic
agents.•Copper complexes are endogenously biocompatible and exhibit reduced side …

Cu homeostasis in bacteria: the ins and outs

A Andrei, Y Öztürk, B Khalfaoui-Hassani, J Rauch… - Membranes, 2020 - mdpi.com
Copper (Cu) is an essential trace element for all living organisms and used as cofactor in
key enzymes of important biological processes, such as aerobic respiration or superoxide …

Intracellular Copper Does Not Catalyze the Formation of Oxidative DNA Damage in Escherichia coli

L Macomber, C Rensing, JA Imlay - Journal of bacteriology, 2007 - Am Soc Microbiol
Because copper catalyzes the conversion of H2O2 to hydroxyl radicals in vitro, it has been
proposed that oxidative DNA damage may be an important component of copper toxicity …

DSB proteins and bacterial pathogenicity

B Heras, SR Shouldice, M Totsika… - Nature Reviews …, 2009 - nature.com
If DNA is the information of life, then proteins are the machines of life—but they must be
assembled and correctly folded to function. A key step in the protein-folding pathway is the …