Traditional organic antimicrobials mainly act on specific biochemical processes such as
replication, transcription and translation. However, the emergence and wide spread of …

Circular RNAs (circRNAs) are a class of single-stranded closed RNA molecules that are
formed by precursor mRNA back-splicing or skipping events of thousands of genes in …

Pyrazolone is a well-known influential synthon for the synthesis of many molecules which
hold remarkable potential in the advancement of functional materials, coordination …

Besides the critical functions in hemostasis, thrombosis and the wounding process, platelets
have been increasingly identified as active players in various processes in tumorigenesis …

This study reports an efficient and convenient click chemistry synthesis of a novel series of
phthalimide scaffold linked to 1, 2, 3 triazole ring and terminal lipophilic fragments …

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are used clinically
as target therapies for lung cancer patients, but the occurrence of acquired drug resistance …

Tyrosinase is a bifunctional polyphenol oxidase (PPO), catalyzing two oxidative reactions:
monophenols to o-quinones (monophenolase activity) and o-diphenols to oquinones …

A novel series of phthalimide-1, 2, 3-trizole hybrids linked to benzyl ring containing different
substituents were synthesized and evaluated for their tyrosinase inhibitory activity (inhibitory …

In the present research work, we prepared N-substituted phthalimide, 2-(-(2-(2-(2-(1, 3-
dioxoisoindoline-2-yl-ethylamino) ethylamino) ethyl) isoindoline-1, 3-dione (DEEI) and its …

Lung cancer is the leading cause of cancer-associated deaths worldwide. In particular, non-
small-cell lung cancer (NSCLC) cells harboring epidermal growth factor receptor (EGFR) …