β-Defensins: multifunctional modulators of infection, inflammation and more?

F Semple, JR Dorin - Journal of innate immunity, 2012 - karger.com
Defensins comprise one of the largest groups of host defence peptides, present throughout
evolution, in fungi and flowering plants as well as in invertebrates and vertebrates. These …

Human β-defensins

M Pazgier, DM Hoover, D Yang, W Lu… - Cellular and Molecular …, 2006 - Springer
The last decade led to the discovery and characterization of several human β-defensins.
Analysis of genomic information indicates that the number of β-defensin-like molecules …

Human defensins

JJ Schneider, A Unholzer, M Schaller… - Journal of molecular …, 2005 - Springer
Antimicrobial peptides are small, cationic, amphiphilic peptides of 12–50 amino acids with
microbicidal activity against both bacteria and fungi. The eukaryotic antimicrobial peptides …

A re-evaluation of the role of host defence peptides in mammalian immunity

DME Bowdish, DJ Davidson… - Current Protein and …, 2005 - ingentaconnect.com
Host defence peptides are found in all classes of life and are a fundamental component of
the innate immune response. Initially it was believed that their sole role in innate immunity …

[HTML][HTML] The role of toll-like receptors in the pathogenesis and treatment of dermatological disease

JE McInturff, RL Modlin, J Kim - Journal of Investigative Dermatology, 2005 - Elsevier
Toll-like receptors (TLR) are crucial players in the innate immune response to microbial
invaders. These receptors are expressed on immune cells, such as monocytes …

Interactions among stratum corneum defensive functions

PM Elias, EH Choi - Experimental dermatology, 2005 - Wiley Online Library
With the exception of vitamin D production, virtually all epidermal functions can be
considered as protective, or more specifically, as defensive in nature (1). Yet, the term …

Synthesis of γ-aminobutyric acid (GABA) by Lactobacillus plantarum DSM19463: functional grape must beverage and dermatological applications

R Di Cagno, F Mazzacane, CG Rizzello… - Applied microbiology …, 2010 - Springer
Agriculture surplus were used as substrates to synthesize γ-aminobutyric acid (GABA) by
Lactobacillus plantarum DSM19463 for the manufacture of a functional beverage or as a …

Low molecular weight hyaluronic acid increases the self-defense of skin epithelium by induction of β-defensin 2 via TLR2 and TLR4

S Gariboldi, M Palazzo, L Zanobbio… - The Journal of …, 2008 - journals.aai.org
In sites of inflammation or tissue injury, hyaluronic acid (HA), ubiquitous in the extracellular
matrix, is broken down into low mw HA (LMW-HA) fragments that have been reported to …

The skin microbiome: is it affected by UV-induced immune suppression?

VK Patra, SN Byrne, P Wolf - Frontiers in microbiology, 2016 - frontiersin.org
Human skin apart from functioning as a physical barricade to stop the entry of pathogens,
also hosts innumerable commensal organisms. The skin cells and the immune system …

Antiinflammatory peptides: current knowledge and promising prospects

M Dadar, Y Shahali, S Chakraborty, M Prasad… - Inflammation …, 2019 - Springer
Background Inflammation is part of the regular host reaction to injury or infection caused by
toxic factors, pathogens, damaged cells, irritants, and allergens. Antiinflammatory peptides …