The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders

ETC Lippard, CB Nemeroff - American journal of psychiatry, 2023 - psychiatryonline.org
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

Neurobiology of early life adversity: A systematic review of meta-analyses towards an integrative account of its neurobiological trajectories to mental disorders

Y Hakamata, Y Suzuki, H Kobashikawa… - Frontiers in …, 2022 - Elsevier
Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of developing mental disorders in later life. However, no review has …

Child maltreatment and long-term physical and mental health outcomes: an exploration of biopsychosocial determinants and implications for prevention

D Mehta, AB Kelly, KR Laurens, D Haslam… - Child Psychiatry & …, 2021 - Springer
Child maltreatment rates remain unacceptably high and rates are likely to escalate as
COVID-related economic problems continue. A comprehensive and evidence-building …

Impact of early life adversities on human brain functioning: A coordinate-based meta-analysis

EJ Kraaijenvanger, TM Pollok, M Monninger… - Neuroscience & …, 2020 - Elsevier
The detrimental impact of early life adversities (ELAs; entailing pre-and postnatal
experiences) on the developing brain has been well established. By inducing neural …

Biological bases of suicidal behaviours: A narrative review

A Lengvenyte, I Conejero, P Courtet… - European journal of …, 2021 - Wiley Online Library
Suicidal behaviour is a multifaceted phenomenon that concerns all human populations. It
has been suggested that a complex interaction between the individual genetic profile and …

Childhood trauma, brain structure and emotion recognition in patients with schizophrenia and healthy participants

KI Rokita, L Holleran, MR Dauvermann… - Social cognitive and …, 2020 - academic.oup.com
Childhood trauma, and in particular physical neglect, has been repeatedly associated with
lower performance on measures of social cognition (eg emotion recognition tasks) in both …

Transdiagnostic analysis of adverse childhood experiences and their association with psychopathology–A TRANS-D conform study

S Goerigk, MA Reinhard, BB Barton, G Burkhardt… - Psychiatry …, 2023 - Elsevier
Transdiagnostic approaches challenge traditional psychiatric classification systems.
Adverse childhood experiences (ACE) represent a transdiagnostic risk factor for …

Emotion dysregulation in borderline personality disorder: a fronto–limbic imbalance?

M Sicorello, C Schmahl - Current opinion in psychology, 2021 - Elsevier
Borderline personality disorder is most consistently characterized as a disorder of the
experience and regulation of emotions. Neuropathological models have predominantly …

The impact of psychosocial adversity on brain and behaviour: an overview of existing knowledge and directions for future research

N Vaidya, AF Marquand, F Nees, S Siehl… - Molecular …, 2024 - nature.com
Environmental experiences play a critical role in shaping the structure and function of the
brain. Its plasticity in response to different external stimuli has been the focus of research …

Borderline personality disorder: a comprehensive review of diagnosis and clinical presentation, etiology, treatment, and current controversies

F Leichsenring, P Fonagy, N Heim… - World …, 2024 - Wiley Online Library
Borderline personality disorder (BPD) was introduced in the DSM‐III in 1980. From the DSM‐
III to the DSM‐5, no major changes have occurred in its defining criteria. The disorder is …