Epidemiological overview of multidimensional chromosomal and genome toxicity of cannabis exposure in congenital anomalies and cancer development

AS Reece, GK Hulse - Scientific reports, 2021 - nature.com
Cannabis and cannabinoids are implicated in multiple genotoxic, epigenotoxic and
chromosomal-toxic mechanisms and interact with several morphogenic pathways, likely …

Cannabis for cancer–illusion or the tip of an iceberg: a review of the evidence for the use of Cannabis and synthetic cannabinoids in oncology

I Turgeman, G Bar-Sela - Expert Opinion on Investigational Drugs, 2019 - Taylor & Francis
Introduction: A flowering plant of variegated ingredients and psychoactive qualities,
Cannabis has long been used for medicinal and recreational purposes. Regulatory …

Global patterns in testicular cancer incidence and mortality in 2020

A Znaor, NE Skakkebaek… - … journal of cancer, 2022 - Wiley Online Library
With 74 500 new cases worldwide in 2020, testicular cancer ranks as the 20th leading
cancer type, but is the most common cancer in young men of European ancestry. While …

Trends in cancer incidence in US adolescents and young adults, 1973-2015

AR Scott, KC Stoltzfus, LT Tchelebi… - JAMA network …, 2020 - jamanetwork.com
Importance Previous studies have demonstrated that adolescents and young adults (AYAs)
with cancer are a distinct cancer population; however, research on long-term …

Cannabinoid and substance relationships of European congenital anomaly patterns: a space-time panel regression and causal inferential study

AS Reece, GK Hulse - Environmental Epigenetics, 2022 - academic.oup.com
Abstract With reports from Australia, Canada, USA, Hawaii and Colorado documenting a link
between cannabis and congenital anomalies (CAs), this relationship was investigated in …

Pharmacological potential of varinic-, minor-, and acidic phytocannabinoids

R Franco, R Rivas-Santisteban, I Reyes-Resina… - Pharmacological …, 2020 - Elsevier
While natural Δ 9-tetrahidrocannabinol (Δ 9 THC), cannabidiol (CBD), and their therapeutic
potential have been extensively researched, some cannabinoids have been less extensively …

Causal inference multiple imputation investigation of the impact of cannabinoids and other substances on ethnic differentials in US testicular cancer incidence

AS Reece, GK Hulse - BMC Pharmacology and Toxicology, 2021 - Springer
Background Ethnic differences in testicular cancer rates (TCRs) are recognized
internationally. Cannabis is a known risk factor for testicular cancer (TC) in multiple studies …

[HTML][HTML] Cannabinoid exposure as a major driver of pediatric acute lymphoid Leukaemia rates across the USA: Combined geospatial, multiple imputation and causal …

AS Reece, GK Hulse - BMC cancer, 2021 - Springer
Background Acute lymphoid leukaemia (ALL) is the commonest childhood cancer whose
incidence is rising in many nations. In the USA, between 1975 and 2016, ALL rates (ALLRs) …

Impacts of cannabinoid epigenetics on human development: reflections on Murphy et. al.'cannabinoid exposure and altered DNA methylation in rat and human sperm' …

AS Reece, GK Hulse - Epigenetics, 2019 - Taylor & Francis
Recent data from the Kollins lab ('Cannabinoid exposure and altered DNA methylation in rat
and human sperm'Epigenetics 2018; 13: 1208–1221) indicated epigenetic effects of …

State trends of cannabis liberalization as a causal driver of increasing testicular cancer rates across the USA

AS Reece, GK Hulse - … Journal of Environmental Research and Public …, 2022 - mdpi.com
Background. The cause of the worldwide doubling-tripling of testicular cancer rates (TCRs)
in recent decades is unknown. Previous cohort studies associated cannabis use with TCR …