Background Spinal cord injury (SCI) is the damage to the spinal cord that can lead to
temporary or permanent loss of function due to injury to the nerve. The SCI patients are often …

Identified 50 years ago, mesenchymal stromal/stem cells (MSCs) immediately generated a
substantial interest among the scientific community because of their differentiation plasticity …

The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …

Various source-derived mesenchymal stem cells (MSCs) have been considered for cell
therapeutics in incurable diseases. To characterize MSCs from different sources, we …

Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into
mesenchymal lineages and that can be isolated from various tissues and easily cultivated in …

Mesenchymal stem/stromal cells (MSCs) can regenerate tissues by direct differentiation or
indirectly by stimulating angiogenesis, limiting inflammation, and recruiting tissue-specific …

Hematopoietic stem and progenitor cells (HSPC) reside in the bone marrow (BM) niche and
serve as a reservoir for mature blood cells throughout life. Aging in the BM is characterized …

The use of fetal bovine serum (FBS) as a cell culture supplement is discouraged by
regulatory authorities to limit the risk of zoonoses and xenogeneic immune reactions in the …

Mesenchymal stromal cells (MSC) emerged as highly attractive in cell-based regenerative
medicine. Initially thought to provide cells capable of differentiation towards mesenchymal …

Human umbilical cord blood (CB) is a potential source for mesenchymal stem cells (MSC)
capable of forming specific tissues, for example, bone, cartilage, or muscle. However …