Glioblastoma (GB) is a highly malignant primary brain tumor with limited treatment options
and poor prognosis. Despite current treatment approaches, including surgical resection …

Background: Focused ultrasound (FUS) in combination with microbubbles has recently
shown great promise in facilitating blood-brain barrier (BBB) opening for drug delivery and …

Purpose Brain tumors, particularly glioblastoma multiforme (GBM), present significant
prognostic challenges despite multimodal therapies, including surgical resection …

Background: The blood-brain barrier (BBB) is a major bottleneck in delivering therapeutics
to the brain. Treatment strategies to transiently open this barrier include focused ultrasound …

Acoustic cavitation plays a critical role in various biomedical applications. However,
uncontrolled cavitation can lead to undesired damage to healthy tissues. Therefore, real …

Focused ultrasound (FUS) is an emerging noinvasive technique for neuromodulation in the
central nervous system (CNS). To evaluate the effects of FUS-induced neuromodulation …

Focused ultrasound (FUS) combined with circulating microbubbles (MBs) can be employed
for non-invasive, localized agent delivery across the blood-brain barrier (BBB). Previous …

A 2012 review of therapeutic ultrasound was published to educate researchers and
physicians on potential applications and concerns for unintended bioeffects (doi …

Focused ultrasound-mediated opening of the blood-brain barrier offers a great opportunity to
deliver therapeutics into hard-to-treat brain tumors such as glioblastoma multiforme or …

Passive cavitation imaging (PCI) is an effective technique for monitoring high intensity
focused ultrasound (HIFU) procedure due to the correlation between cavitation activities and …