Glucose isomerase (GI, also known as xylose isomerase) reversibly isomerizes D-glucose
and D-xylose to D-fructose and D-xylulose, respectively. GI plays an important role in sugar …

The International Year of Crystallography saw the number of macromolecular structures
deposited in the Protein Data Bank cross the 100000 mark, with more than 90000 of these …

Neutron protein crystallography is a powerful tool for investigating protein chemistry
because it directly locates hydrogen atom positions in a protein structure. The visibility of …

Glucose isomerase (GI) is extensively used in the food industry for production of high-
fructose corn syrup and for the production of biofuels and other renewable chemicals …

FTIR and NMR spectra were measured in parallel for specific two-components mixtures of
various proteins with different sugar molecules, such as arabinose, glucose, and sucrose. In …

Metal cofactors are essential for catalysis and enable countless conversions in nature.
Interestingly, the metal cofactor is not always static but mobile with movements of more than …

Isomerases are enzymes that induce physical changes in a molecule without affecting the
original molecular formula. Among this class of enzymes, xylose isomerases (XIs) are the …

New Cδ–H⋯ O histidine hydrogen bonding interactions in various proteins are identified by
neutron diffraction and computationally characterized. Neutron diffraction data shows …

Human transthyretin has an intrinsic tendency to form amyloid fibrils and is heavily
implicated in senile systemic amyloidosis. Here, detailed neutron structural studies of …

Neutron diffraction techniques permit direct determination of the hydrogen (H) and
deuterium (D) positions in crystal structures of biological macromolecules at resolutions of∼ …