Iron deficiency in heart failure: mechanisms and pathophysiology
RIS Alnuwaysir, MF Hoes, DJ van Veldhuisen… - Journal of clinical …, 2021 - mdpi.com
Iron is an essential micronutrient for a myriad of physiological processes in the body beyond
erythropoiesis. Iron deficiency (ID) is a common comorbidity in patients with heart failure …
erythropoiesis. Iron deficiency (ID) is a common comorbidity in patients with heart failure …
Diagnosing anemia: Challenges selecting methods, addressing underlying causes, and implementing actions at the public health level
MN Garcia‐Casal, O Dary, ME Jefferds… - Annals of the New …, 2023 - Wiley Online Library
Accurate and affordable tools for diagnosing anemia and its main determinants are essential
for understanding the magnitude and distribution of the problem and the appropriate …
for understanding the magnitude and distribution of the problem and the appropriate …
A new artificial intelligence approach using extreme learning machine as the potentially effective model to predict and analyze the diagnosis of anemia
The procedure to diagnose anemia is time-consuming and resource-intensive due to the
existence of a multitude of symptoms that can be felt physically or seen visually. Anemia also …
existence of a multitude of symptoms that can be felt physically or seen visually. Anemia also …
Dietary approaches to iron deficiency prevention in childhood—a critical public health issue
JP Chouraqui - Nutrients, 2022 - mdpi.com
Iron is an essential nutrient, and individual iron status is determined by the regulation of iron
absorption, which is driven by iron requirements. Iron deficiency (ID) disproportionately …
absorption, which is driven by iron requirements. Iron deficiency (ID) disproportionately …
Empagliflozin effects on iron metabolism as a possible mechanism for improved clinical outcomes in non-diabetic patients with systolic heart failure
CE Angermann, CG Santos-Gallego… - Nature Cardiovascular …, 2023 - nature.com
Abstract Sodium-glucose co-transporter-2 (SGLT2) inhibitors improve clinical outcomes in
patients with heart failure (HF), but mechanisms of action are incompletely understood. In …
patients with heart failure (HF), but mechanisms of action are incompletely understood. In …
New era in the treatment of iron deficiency anaemia using trimaltol iron and other lipophilic iron chelator complexes: historical perspectives of discovery and future …
GJ Kontoghiorghes, A Kolnagou, T Demetriou… - International Journal of …, 2021 - mdpi.com
The trimaltol iron complex (International Non-proprietary Name: ferric maltol) was originally
designed, synthesised, and screened in vitro and in vivo in 1980–1981 by Kontoghiorghes …
designed, synthesised, and screened in vitro and in vivo in 1980–1981 by Kontoghiorghes …
[HTML][HTML] Metformin alleviates hepatic iron overload and ferroptosis through AMPK-ferroportin pathway in HFD-induced NAFLD
F Yue, Y Shi, S Wu, L Xing, D He, L Wei, A Qiu… - Iscience, 2023 - cell.com
Metformin prevents progression of non-alcoholic fatty liver disease (NAFLD). However, the
potential mechanism is not entirely understood. Ferroptosis, a recently recognized …
potential mechanism is not entirely understood. Ferroptosis, a recently recognized …
Association between iron status markers and kidney outcome in patients with chronic kidney disease
H Fujisawa, M Nakayama, N Haruyama, A Fukui… - Scientific reports, 2023 - nature.com
Several studies conducted in patients with various stages of chronic kidney disease (CKD)
have investigated the association of iron status markers, such as transferrin saturation …
have investigated the association of iron status markers, such as transferrin saturation …
[HTML][HTML] Hemoglobin distributions and prevalence of anemia in a multiethnic United States pregnant population
Background Few normative longitudinal hemoglobin data are available to estimate the
prevalence and risk factors for anemia among a multiethnic United States pregnant …
prevalence and risk factors for anemia among a multiethnic United States pregnant …
Positive or U-shaped association of elevated hemoglobin concentration levels with metabolic syndrome and metabolic components: findings from Taiwan biobank and …
VJ Timoteo, KM Chiang, WH Pan - Nutrients, 2022 - mdpi.com
Iron overnutrition has been implicated with a higher risk of developing metabolic and
cardiovascular diseases, including metabolic syndrome (MetS), whereas iron deficiency …
cardiovascular diseases, including metabolic syndrome (MetS), whereas iron deficiency …