A number of new tuberculosis (TB) vaccines have been or are entering clinical trials, which
include genetically modified mycobacteria, mycobacterial antigens delivered by viral …

Human infection with Mycobacterium tuberculosis can progress to active disease, be
contained as latent infection, or be eradicated by the host response. Tuberculosis …

Background BCG vaccination provides incomplete protection against tuberculosis in infants.
A new vaccine, modified Vaccinia Ankara virus expressing antigen 85A (MVA85A), was …

There is a need for safe and effective platform vaccines to protect against coronavirus
disease 2019 (COVID-19) and other infectious diseases. In this randomized, double …

Vaccines to protect against tuberculosis (TB) are urgently needed. We performed a case–
control analysis to identify immune correlates of TB disease risk in Bacille Calmette–Guerin …

Rationale: Immunogenicity of new tuberculosis (TB) vaccines is commonly assessed by
measuring the frequency and cytokine expression profile of T cells. Objectives: We tested …

Children represent both a clinically important population susceptible to tuberculosis and a
key group in whom to study intrinsic and vaccine-induced mechanisms of protection. After …

Objective: To determine whether a multiple-dose series of an inactivated whole cell
mycobacterial vaccine, Mycobacterium vaccae, can prevent HIV-associated tuberculosis …

Tuberculosis (TB) disease caused by Mycobacterium tuberculosis (M. tb) remains one of the
leading infectious causes of death and disease throughout the world. The only licensed …

Microneedles (MNs) are designed to specifically target the outermost, skin barrier layer, the
stratum corneum, creating transient pathways for minimally invasive transcutaneous …