The human lens: an antioxidant-dependent tissue revealed by the role of caffeine

M Ruiss, O Findl, M Kronschläger - Ageing research reviews, 2022 - Elsevier
Cataract is the leading cause of blindness worldwide and surgery is the only option to treat
the disease. Although the surgery is considered to be relatively safe, complications may …

Emerging roles of oxidative stress in the pathogenesis of pseudoexfoliation syndrome

S Mastronikolis, M Pagkalou… - Experimental and …, 2022 - spandidos-publications.com
Pseudoexfoliation syndrome (PEXS) is a systemic disease caused by defects in the
extracellular matrix (ECM) remodelling process leading to the chronic deposition of …

Hallmarks of lens aging and cataractogenesis

TFL Wishart, M Flokis, DY Shu, SJ Das… - Experimental Eye …, 2021 - Elsevier
Lens homeostasis and transparency are dependent on the function and intercellular
communication of its epithelia. While the lens epithelium is uniquely equipped with …

Metabolomics reveals differences in aqueous humor composition in patients with and without pseudoexfoliation syndrome

DA Dmuchowska, K Pietrowska, P Krasnicki… - Frontiers in Molecular …, 2021 - frontiersin.org
Pseudoexfoliation syndrome (XFS) is stress-or inflammation-induced elastosis accompanied
by excessive production of microfibrils and their deposition in the anterior segment of the …

[HTML][HTML] Oxidative Stress in Cataract Formation: Is There a Treatment Approach on the Horizon?

J Li, F Buonfiglio, Y Zeng, N Pfeiffer, A Gericke - Antioxidants, 2024 - mdpi.com
Cataracts, a leading cause of blindness worldwide, are closely linked to oxidative stress-
induced damage to lens epithelial cells (LECs). Key factors contributing to cataract formation …

Protective effect of apelin-13 in lens epithelial cells via inhibiting oxidative stress-induced apoptosis

X Li, C Gu, Q Hu, L Wang, Y Zhang, L Yu - BMC ophthalmology, 2024 - Springer
Background It is widely accepted that glaucoma-induced oxidative stress expedites
cataracts' process. Therefore, we examined the effects of apelin-13 against oxidative stress …

Emerging roles of oxidative stress in the pathogenesis of pseudoexfoliation syndrome

M Pagkalou, P Plotas, K Kagkelaris… - Experimental and …, 2022 - search.proquest.com
Pseudoexfoliation syndrome (PEXS) is a systemic disease caused by defects in the
extracellular matrix (ECM) remodelling process leading to the chronic deposition of …

[HTML][HTML] Основы диабетического катарактогенеза и перспективные пути его фармакологической коррекции

АА Спасов, ЛВ Науменко… - Acta Biomedica Scientifica, 2021 - cyberleninka.ru
Среди поздних осложнений сахарного диабета отдельно выделяется катаракта,
приводящая к снижению зрительных функций и в дальнейшем-к слепоте. Несмотря на …