Improved understanding of differences in kidney disease epidemiology, management and
outcomes in men and women could help nephrologists to better meet the needs of their …

Acute kidney injury (AKI) is defined as a decrease in kidney function within hours, which
encompasses both injury and impairment of renal function. AKI is not considered a …

Chronic kidney disease affects 10% of the population with notable differences in ethnic and
sex-related susceptibility to kidney injury and disease. Kidney dysfunction leads to …

Background Single-cell sequencing technologies have advanced our understanding of
kidney biology and disease, but the loss of spatial information in these datasets hinders our …

In both humans and mice, repair of acute kidney injury is worse in males than in females.
Here, we provide evidence that this sexual dimorphism results from sex differences in …

Background Female sex has been included as a risk factor in models developed to predict
the development of AKI. In addition, the commentary to the Kidney Disease Improving Global …

Aristolochic acid nephropathy (AAN) is characterized by acute proximal tubule necrosis and
immune cell infiltration, contributing to the global burden of chronic kidney disease and …

Hyperuricemia, or elevated serum urate, causes urate kidney stones and gout and also
increases the incidence of many other conditions including renal disease, cardiovascular …

Background The association of several comorbidities, including diabetes mellitus,
hypertension, cardiovascular disease, heart failure and chronic kidney or liver disease, with …

Background: Acute kidney injury (AKI) following non-cardiac surgery is common and has
substantial health impact. Preclinical and clinical studies examining the influence of sex on …