Is the global prevalence rate of adult mental illness increasing? Systematic review and meta‐analysis

D Richter, A Wall, A Bruen… - Acta Psychiatrica …, 2019 - Wiley Online Library
Objectives The question whether mental illness prevalence rates are increasing is a
controversially debated topic. Epidemiological articles and review publications that look into …

[HTML][HTML] Does aerobic exercise effect pain sensitisation in individuals with musculoskeletal pain? A systematic review

L Tan, FM Cicuttini, J Fairley, L Romero… - BMC musculoskeletal …, 2022 - Springer
Pain sensitisation plays a major role in musculoskeletal pain. However, effective treatments
are limited, and although there is growing evidence that exercise may improve pain …

Genome-wide association study of medication-use and associated disease in the UK Biobank

Y Wu, EM Byrne, Z Zheng, KE Kemper, L Yengo… - Nature …, 2019 - nature.com
Genome-wide association studies (GWASs) of medication use may contribute to
understanding of disease etiology, could generate new leads relevant for drug discovery …

Off-label indications for antidepressants in primary care: descriptive study of prescriptions from an indication based electronic prescribing system

J Wong, A Motulsky, M Abrahamowicz, T Eguale… - bmj, 2017 - bmj.com
Objective To examine off-label indications for antidepressants in primary care and determine
the level of scientific support for off-label prescribing. Design Descriptive study of …

Ketamine treatment for depression: opportunities for clinical innovation and ethical foresight

I Singh, C Morgan, V Curran, D Nutt, A Schlag… - The Lancet …, 2017 - thelancet.com
We present a review and analysis of the ethical considerations in off-label ketamine use for
severe, treatment-resistant depression. The analysis of ethical considerations is …

Approaches for discontinuation versus continuation of long‐term antidepressant use for depressive and anxiety disorders in adults

E Van Leeuwen, ML van Driel… - Cochrane Database …, 2021 - cochranelibrary.com
Background Depression and anxiety are the most frequent indication for which
antidepressants are prescribed. Long‐term antidepressant use is driving much of the …

Measures of depression and risk of type 2 diabetes: A systematic review and meta-analysis

EA Graham, SS Deschênes, MN Khalil, S Danna… - Journal of affective …, 2020 - Elsevier
Background Depression is associated with an increased risk of type 2 diabetes. This study
aimed to determine whether the association between depression and incident type 2 …

Drug treatment strategies for depression in Parkinson disease

M Ryan, CV Eatmon, JT Slevin - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Depression is a common non-motor symptom in Parkinson disease (PD),
occurring in approximately 20% of patients with PD. While depression can occur anytime in …

The association of antidepressant drug usage with cognitive impairment or dementia, including Alzheimer disease: A systematic review and meta‐analysis

J Moraros, C Nwankwo, SB Patten… - Depression and …, 2017 - Wiley Online Library
Objective To determine if antidepressant drug usage is associated with cognitive impairment
or dementia, including Alzheimer disease (AD). Method We conducted a systematic search …

Antidiabetes agents and incident depression: a nationwide population-based study

LV Kessing, HC Rytgaard, CT Ekstrøm, FK Knop… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Diabetes is associated with an increased risk of depression. Some antidiabetes
agents, specifically metformin and pioglitazone, have been suggested to have beneficial …