Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead

A Grattoni, G Korbutt, AA Tomei, AJ García… - Nature Reviews …, 2024 - nature.com
Type 1 diabetes mellitus (T1DM) is a growing global health concern that affects
approximately 8.5 million individuals worldwide. T1DM is characterized by an autoimmune …

Advancements in innate immune regulation strategies in islet transplantation

K Duan, J Liu, J Zhang, T Chu, H Liu, F Lou… - Frontiers in …, 2024 - frontiersin.org
As a newly emerging organ transplantation technique, islet transplantation has shown the
advantages of minimal trauma and high safety since it was first carried out. The proposal of …

Direct Radiolabeling of Trastuzumab-Targeting Triblock Copolymer Vesicles with 89Zr for Positron Emission Tomography Imaging

V Kozlovskaya, M Ducharme, M Dolmat… - …, 2023 - ACS Publications
Radiolabeled drug nanocarriers that can be easily imaged via positron emission
tomography (PET) are highly significant as their in vivo outcome can be quantitatively PET …

From stem cells to pancreatic β-cells: strategies, applications, and potential treatments for diabetes

X Feng, H Zhang, S Yang, D Cui, Y Wu, X Qi… - Molecular and Cellular …, 2024 - Springer
Loss and functional failure of pancreatic β-cells results in disruption of glucose homeostasis
and progression of diabetes. Although whole pancreas or pancreatic islet transplantation …

Precision Biomaterials for Modulating Regulatory T cells

P Hadley - 2024 - escholarship.org
Over the past few decades, regulatory T cell (Treg) therapy has gained traction for the
treatment of autoimmunity, transplant rejection, and other inflammatory diseases. A …

[图书][B] Strategies for HER2 Targeted Pet Imaging

MA Ducharme - 2023 - search.proquest.com
Breast cancer is one of the most common and deadly cancers diagnosed in women each
year. The HER2-positive subtype of breast cancer is associated with poor prognosis and …