The inclusion of peptide retention time prediction promises to remove peptide identification
ambiguity in complex liquid chromatography–mass spectrometry identification workflows …

Dried blood spot (DBS) sampling is a method with advantages over conventional blood
sampling in relation to collection, cost, storage, and transportation. Such advantages have …

Multi-omics approaches including proteomics analyses are becoming an integral
component of precision medicine. As clinical proteomics studies gain momentum and their …

The goal of paleoproteomics is to characterize proteins from specimens that have been
subjected to the degrading and obscuring effects of time, thus obtaining biological …

Precision medicine focuses on adapting care to the individual profile of patients, for
example, accounting for their unique genetic makeup. Being able to account for the effect of …

Purpose Newborn screening using dried blood spot (DBS) samples for the targeted
measurement of metabolites and nucleic acids has made a substantial contribution to public …

Alternative splicing can lead to distinct protein isoforms. These can have different functions
in specific cells and tissues or in different developmental stages. In this study, we explored …

Variant peptides resulting from single nucleotide polymorphisms (SNPs) can lead to
aberrant protein functions and have translational potential for disease diagnosis and …

The importance of single nucleotide polymorphisms (SNPs) is well known in diseases but
which ones are translated to form single amino acid variant (SAV or variant) is not studied in …

Gene expression is a multi-step transformation of biological information from its storage form
(DNA) into functional forms (protein and some RNAs). Regulatory activities at each step of …