[HTML][HTML] The spectrum of sex differences in cancer

JB Rubin - Trends in cancer, 2022 - cell.com
Sex differences in cellular and systems biology have been evolutionarily selected to
optimize reproductive success in all species with little (sperm) and big (ova) gamete …

[HTML][HTML] Sex shapes gut–microbiota–brain communication and disease

KC Hokanson, C Hernández, GE Deitzler… - Trends in …, 2024 - cell.com
Research into the microbiota–gut–brain axis (MGBA) has entered a golden age, raising the
hope that therapeutics acting on it may offer breakthroughs in the treatment of many …

[图书][B] Invisible women: Data bias in a world designed for men

CC Perez - 2019 - books.google.com
Caroline Criado Perez's Invisible Women: Data Bias in a World Designed for Men is a
landmark, prize-winning, international bestselling examination of how a gender gap in data …

Sex as a biological variable: a 5-year progress report and call to action

ME Arnegard, LA Whitten, C Hunter… - Journal of Women's …, 2020 - liebertpub.com
A little over 5 years ago, the US National Institutes of Health (NIH) announced the intention
to develop policies to require applicants to report plans to balance male and female cells …

Polygenic risk scores: An overview from bench to bedside for personalised medicine

B Cross, R Turner, M Pirmohamed - Frontiers in Genetics, 2022 - frontiersin.org
Since the first polygenic risk score (PRS) in 2007, research in this area has progressed
significantly. The increasing number of SNPs that have been identified by large scale GWAS …

Sex differences in mortality among binational cohort of people with chronic kidney disease: population based data linkage study

NL De La Mata, B Rosales, G MacLeod, PJ Kelly… - bmj, 2021 - bmj.com
Objective To evaluate sex differences in mortality among people with kidney failure
compared with the general population. Design Population based cohort study using data …

Predicting human fetal drug exposure through maternal‐fetal PBPK modeling and in vitro or ex vivo studies

A Balhara, AR Kumar… - The Journal of Clinical …, 2022 - Wiley Online Library
Medication (drug) use in human pregnancy is prevalent. Determining fetal safety and
efficacy of drugs is logistically challenging. However, predicting (not measuring) fetal drug …

Let's talk about sex—biological sex is underreported in biomaterial studies

BD James, P Guerin, JB Allen - Advanced healthcare materials, 2021 - Wiley Online Library
Precision medicine aims to better individualize healthcare. It requires that biomaterials be
designed for the physiological characteristics of a specific patient. To make this a reality …

Evaluating the evidence for sex differences: a scoping review of human neuroimaging in psychopharmacology research

KA Duffy, CN Epperson - Neuropsychopharmacology, 2022 - nature.com
Although sex differences in psychiatric disorders abound, few neuropsychopharmacology
(NPP) studies consider sex as a biological variable (SABV). We conducted a scoping review …

Variability in variability: does variation in morphological and physiological traits differ between men and women?

LG Halsey, GP Esteves… - Royal Society Open …, 2023 - royalsocietypublishing.org
Many researchers presume greater variability between female participants than between
males due to the menstrual cycle. This view has encouraged a sex bias in health and …