Quality control of human pluripotent stem cell colonies by computational image analysis using convolutional neural networks
A Mamaeva, O Krasnova, I Khvorova, K Kozlov… - International Journal of …, 2022 - mdpi.com
Human pluripotent stem cells are promising for a wide range of research and therapeutic
purposes. Their maintenance in culture requires the deep control of their pluripotent and …
purposes. Their maintenance in culture requires the deep control of their pluripotent and …
Understanding cell culture dynamics: a tool for defining protocol parameters for improved processes and efficient manufacturing using human embryonic stem cells
JWT Kusena, M Shariatzadeh, RJ Thomas… - …, 2021 - Taylor & Francis
Standardization is crucial when culturing cells including human embryonic stem cells
(hESCs) which are valuable for therapy development and disease modeling. Inherent issues …
(hESCs) which are valuable for therapy development and disease modeling. Inherent issues …
Induced pluripotent stem cells in pediatric research and clinical translation
D Uçkan-Çetinkaya, KH Haider - Stem Cells: Latest Advances, 2021 - Springer
Reprogramming cells to gain pluripotency or a different lineage has been a breakthrough
enabling disease modeling, drug discovery, toxicity testing, drug repurposing for new …
enabling disease modeling, drug discovery, toxicity testing, drug repurposing for new …
A defined and scalable peptide-based platform for the generation of human pluripotent stem cell-derived astrocytes
S Raman, G Srinivasan, N Brookhouser… - ACS biomaterials …, 2020 - ACS Publications
Astrocytes comprise the most abundant cell type in the central nervous system (CNS) and
play critical roles in maintaining neural tissue homeostasis. In addition, astrocyte dysfunction …
play critical roles in maintaining neural tissue homeostasis. In addition, astrocyte dysfunction …
The importance of cell culture parameter standardization: an assessment of the robustness of the 2102Ep reference cell line
JWT Kusena, M Shariatzadeh, AJ Studd, JR James… - …, 2021 - Taylor & Francis
Work undertaken using the embryonic carcinoma 2102Ep line, highlighted the requirement
for robust, well-characterized and standardized protocols. A systematic approach utilizing …
for robust, well-characterized and standardized protocols. A systematic approach utilizing …
Induzierte pluripotente Stammzellen in der pädiatrischen Forschung und klinischen Umsetzung
D Uçkan-Çetinkaya, KH Haider - Stammzellen: Neueste Fortschritte, 2023 - Springer
Zusammenfassung Die Umprogrammierung von Zellen, um Pluripotenz oder eine andere
Abstammungslinie zu erlangen, ist ein Durchbruch, der die Modellierung von Krankheiten …
Abstammungslinie zu erlangen, ist ein Durchbruch, der die Modellierung von Krankheiten …
[PDF][PDF] Scale-out cultivation of human dermal fibroblasts using robotic cell culture system: comparison of manual and automated processing
FA Fadeyev, DV Sedneva-Lugovets… - Cell Ther …, 2022 - cttjournal.com
Automation of cell cultivation process allows solving the problems of standardization,
reproducibility and cost effectiveness of the large scale manufacturing of cell-based therapy …
reproducibility and cost effectiveness of the large scale manufacturing of cell-based therapy …
Investigating the Role of APOE2 in Alzheimer's Disease Using Human Induced Pluripotent Stem Cell Derived Neurons and Astrocytes
S Raman - 2021 - search.proquest.com
Genome wide association studies (GWAS) have identified polymorphism in the
Apolipoprotein E (APOE) gene to be the most prominent risk factor for Alzheimer's disease …
Apolipoprotein E (APOE) gene to be the most prominent risk factor for Alzheimer's disease …
[PDF][PDF] Optimising process quality and cost for closed, automated and commercial scale manufacture of allogeneic stem cell therapy products
W Mitchell - 2020 - repository.lboro.ac.uk
Embryonic stem cell (ESC) derived therapies offer huge potential for clinical and economic
benefit; however, their development is currently restricted by the suitability of available …
benefit; however, their development is currently restricted by the suitability of available …