Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …

RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

The field of RNA nanotechnology has advanced rapidly during the past decade. A variety of
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …

RNA origami is a framework for the modular design of nanoscaffolds that can be folded from
a single strand of RNA and used to organize molecular components with nanoscale …

MicroRNAs play important roles in regulating the gene expression and life cycle of cancer
cells. In particular, miR-21, an oncogenic miRNA is a major player involved in tumor …

In the last three decades, oligonucleotides have been extensively investigated as probes,
molecular ligands and even catalysts within therapeutic and diagnostic applications. The …

Nucleic acids play a central role in all domains of life, either as genetic blueprints or as
regulators of various biochemical pathways. The 826chemical makeup of ribonucleic acid …

Conspectus Nanotechnology's central goal involves the direct control of matter at the
molecular nanometer scale to build nanofactories, nanomachines, and other devices for …

Human genome sequencing revealed that only~ 1.5% of the DNA sequence coded for
proteins. More and more evidence has uncovered that a substantial part of the 98.5% so …

Our recent advancements in RNA nanotechnology introduced novel nanoscaffolds
(nanorings); however, the potential of their use for biomedical applications was never fully …