Genetic Diversity in Mycobacterium tuberculosis Clinical Isolates and Resulting Outcomes of Tuberculosis Infection and Disease
Tuberculosis claims more human lives than any other bacterial infectious disease and
represents a clear and present danger to global health as new tools for vaccination …
represents a clear and present danger to global health as new tools for vaccination …
The Interplay of Human and Mycobacterium Tuberculosis Genomic Variability
W Correa-Macedo, G Cambri, E Schurr - Frontiers in Genetics, 2019 - frontiersin.org
Tuberculosis (TB), caused by the human pathogens Mycobacterium tuberculosis (Mtb) and
Mycobacterium africanum, has plagued humanity for millennia and remains the deadliest …
Mycobacterium africanum, has plagued humanity for millennia and remains the deadliest …
The global success of Mycobacterium tuberculosis modern Beijing family is driven by a few recently emerged strains
C Zhu, T Yang, J Yin, H Jiang, HE Takiff… - Microbiology …, 2023 - Am Soc Microbiol
Strains of the Mycobacterium tuberculosis complex (MTBC) Beijing family aroused concern
because they were often found in clusters and appeared to be exceptionally transmissible …
because they were often found in clusters and appeared to be exceptionally transmissible …
Revised nomenclature and SNP barcode for Mycobacterium tuberculosis lineage 2
Y Thawornwattana, S Mahasirimongkol… - Microbial …, 2021 - microbiologyresearch.org
Mycobacterium tuberculosis (Mtb) lineage 2 (L2) strains are present globally, contributing to
a widespread tuberculosis (TB) burden, particularly in Asia where both prevalence of TB and …
a widespread tuberculosis (TB) burden, particularly in Asia where both prevalence of TB and …
Analysis of complete genomes of Mycobacterium tuberculosis sublineage 2.1 (Proto-Beijing) revealed the presence of three pe_pgrs3-pe_pgrs4-like genes
OF Davies-Bolorunduro, B Jaemsai, W Ruangchai… - Scientific Reports, 2024 - nature.com
Mycobacterium tuberculosis Complex (MTBC), the etiological agent of tuberculosis (TB),
demonstrates considerable genotypic diversity with distinct geographic distributions and …
demonstrates considerable genotypic diversity with distinct geographic distributions and …
Impact of pathobiological diversity of Mycobacterium tuberculosis on clinical features and lethal outcome of tuberculosis
I Mokrousov, O Pasechnik, A Vyazovaya, I Yarusova… - BMC microbiology, 2022 - Springer
Background Mycobacterium tuberculosis population in Russia is dominated by the notorious
Beijing genotype whose major variants are characterized by contrasting resistance and …
Beijing genotype whose major variants are characterized by contrasting resistance and …
A multi-omics investigation into the mechanisms of hyper-virulence in Mycobacterium tuberculosis
Clinical manifestations of tuberculosis range from asymptomatic infection to a life-
threatening disease such as tuberculous meningitis (TBM). Recent studies showed that the …
threatening disease such as tuberculous meningitis (TBM). Recent studies showed that the …
Screening repurposed antiviral small molecules as antimycobacterial compounds by a lux-based phoP promoter-reporter platform
The emergence of multidrug-resistant strains and hyper-virulent strains of Mycobacterium
tuberculosis are big therapeutic challenges for tuberculosis (TB) control. Repurposing …
tuberculosis are big therapeutic challenges for tuberculosis (TB) control. Repurposing …
Genetic diversity, evolution and drug resistance of Mycobacterium tuberculosis lineage 2
S Atavliyeva, D Auganova, P Tarlykov - Frontiers in Microbiology, 2024 - frontiersin.org
Mycobacterium tuberculosis causes a chronic infectious disease called tuberculosis.
Phylogenetic lineage 2 (L2) of M. tuberculosis, also known as the East Asian lineage, is …
Phylogenetic lineage 2 (L2) of M. tuberculosis, also known as the East Asian lineage, is …
Genetic mechanisms of co-emergence of INH-resistant Mycobacterium tuberculosis strains during the standard course of antituberculosis therapy
K Tafess, TTL Ng, KKG Tam, KSS Leung… - Microbiology …, 2024 - Am Soc Microbiol
The incidence of isoniazid (INH) resistant Mycobacterium tuberculosis is increasing globally.
This study aimed to identify the molecular mechanisms behind the development of INH …
This study aimed to identify the molecular mechanisms behind the development of INH …