The term functionalized isocyanides refers to all those isocyanides in which a neighbouring
functional group can finely tune the reactivity of the isocyano group or can be exploited in …

Multicomponent reactions (MCRs) are extremely popular owing to their facile execution,
high atom-efficiency and the high diversity of products. MCRs can be used to access various …

The history of isocyanide chemistry goes back to the first synthesis of allyl isocyanide by
alkylation of silver cyanide reported by Lieke in 1859. 1 These isomers of cyanides …

Three-component reactions have emerged as useful methods because the combination of
three components to generate new products in a single step is extremely economical …

The chemistry of methyl α-isocyanoacetate (1) was investigated thoroughly in the 1970s,
mainly by the research groups of Schöllkopf and Matsumoto.[1, 4] One particularly powerful …

A palladium-catalyzed imidoylative cycloamidation of N-alkyl-2-isocyanobenzamides with 2,
6-disubstituted aryl iodides, affording unprecedented axially chiral 2-arylquinazolinones …

Isocyanides have a long history in organic chemistry and have been used in all areas, from
academia to industry.[1] It is one of the most versatile and extensively examined stable …

Nitrilium ions have been well-established in organic chemistry for many decades, but recent
developments show them to be far more versatile than hitherto recognized. They are known …

Diversely substituted anilines are prepared by treatment of functionalized arylboronic acids
with a common, inexpensive source of electrophilic nitrogen (H2N-OSO3H, HSA) under …

After a series of careful conditional optimizations and catalyst screenings, a methodology to
prepare isatoic anhydrides through organoselenium-catalyzed selective oxidation of isatins …