Bacterial chitinases (EC 3.2. 1.14) and chitin-binding proteins (CBPs) play a fundamental
role in the degradation of the ubiquitous biopolymer chitin, and the degradation products …

The Francisella pathogenicity island (FPI) is a cluster of 16–19 genes, which is found
duplicated in most of the Francisella genomes that have been sequenced. Although 16 FPI …

The highly infectious bacterium Francisella tularensis is a facultative intracellular pathogen,
whose virulence requires proliferation inside host cells, including macrophages. Here we …

Microorganisms, although being very diverse because they comprise prokaryotic organisms
such as bacteria or eukaryotic organisms such as fungi, all share an essential exodigester …

Background COG0523 proteins are, like the nickel chaperones of the UreG family, part of the
G3E family of GTPases linking them to metallocenter biosynthesis. Even though the first …

Francisella tularensis is a highly virulent gram-negative intracellular bacterium that causes
the zoonotic disease tularemia. Essential for its virulence is the ability to multiply within host …

The Francisella pathogenicity island (FPI) encodes proteins thought to compose a type VI
secretion system (T6SS) that is required for the intracellular growth of Francisella novicida …

Francisella tularensis is a highly infectious, facultative intracellular bacterial pathogen that is
the causative agent of tularemia. Nearly a century ago, researchers observed that tularemia …

Francisella tularensis is one of the most pathogenic pathogens known, especially when
disseminated as a small particle aerosol. Because of this, it was developed into a biological …

Francisella tularensis is a Gram-negative, facultative intracellular bacterium, causing a
severe disease called tularemia. It secretes unusually shaped nanotubular outer membrane …