Among various matrix metalloproteinases (MMPs), MMPs having medium-size S1′ pockets
are established as promising biomolecular targets for executing crucial roles in cancer …

Matrix metalloproteinases (MMPs) serve as prognostic factors in several pathophysiological
conditions, including chronic wounds. Therefore, they are considered important therapeutic …

Background The number of cancer-related deaths is on the increase, combating this deadly
disease has proved difficult owing to resistance and some serious side effects associated …

In this study, the antiproliferative activities of some chalcones and dihydro pyrazole
derivatives in prostate cancer were investigated via the androgen receptor using the QSAR …

This study aimed to test the hypothesis that bioactive peptides can exert multiple bioactivities
at different sites in the gastrointestinal tract. Our previous research identified 33 gastric …

Molecular docking is a structure-based computational technique that plays a major role in
drug discovery. Molecular docking enhances the efficacy of determining the metabolic …

Solid-state magnetocaloric-based magnetic refrigeration offers green and sustainable
refrigeration with improved efficiency, compactness and environmental friendliness …

The structure-property relationship is important in understanding molecular behaviors and
their best-fit areas of applications. 3-(4-hydroxyphenyl) prop-2-en-1-one 4-phenyl Schiff …

Cancer remains a threat to human existence owing the high number of deaths associated
with it. Combating cancer has continued to garner interest from pharmaceutical companies …

Abstract Cyclin-dependent kinase 4 (CDK4) is an important target in designing anticancer
drugs. The activation of CDK4 results in phosphorylation of the retinoblastoma gene product …