[HTML][HTML] m6A modification in coding and non-coding RNAs: roles and therapeutic implications in cancer
N 6-Methyladenosine (m 6 A) RNA modification has emerged in recent years as a new layer
of regulatory mechanism controlling gene expression in eukaryotes. As a reversible …
of regulatory mechanism controlling gene expression in eukaryotes. As a reversible …
N6‐methyladenosine regulatory machinery in plants: composition, function and evolution
H Yue, X Nie, Z Yan, S Weining - Plant Biotechnology Journal, 2019 - Wiley Online Library
Summary N6‐methyladenosine (m6A) RNA methylation, one of the most pivotal internal
modifications of RNA, is a conserved post‐transcriptional mechanism to enrich and regulate …
modifications of RNA, is a conserved post‐transcriptional mechanism to enrich and regulate …
[HTML][HTML] Landscape and regulation of m6A and m6Am methylome across human and mouse tissues
Summary N 6-methyladenosine (m 6 A), the most abundant internal mRNA modification, and
N 6, 2′-O-dimethyladenosine (m 6 Am), found at the first-transcribed nucleotide, are two …
N 6, 2′-O-dimethyladenosine (m 6 Am), found at the first-transcribed nucleotide, are two …
[HTML][HTML] m6A RNA modification modulates PI3K/Akt/mTOR signal pathway in gastrointestinal cancer
Q Zhao, Y Zhao, W Hu, Y Zhang, X Wu, J Lu, M Li… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Methylation at the N6 position of adenosine (m 6 A) is the most prevalent RNA
modification within protein-coding mRNAs in mammals, and it is a reversible modification …
modification within protein-coding mRNAs in mammals, and it is a reversible modification …
m7GHub: deciphering the location, regulation and pathogenesis of internal mRNA N7-methylguanosine (m7G) sites in human
Motivation Recent progress in N7-methylguanosine (m7G) RNA methylation studies has
focused on its internal (rather than capped) presence within mRNAs. Tens of thousands of …
focused on its internal (rather than capped) presence within mRNAs. Tens of thousands of …
[HTML][HTML] Bioinformatics approaches for deciphering the epitranscriptome: recent progress and emerging topics
Post-transcriptional RNA modification occurs on all types of RNA and plays a vital role in
regulating every aspect of RNA function. Thanks to the development of high-throughput …
regulating every aspect of RNA function. Thanks to the development of high-throughput …
[HTML][HTML] m6A Reader: Epitranscriptome Target Prediction and Functional Characterization of N6-Methyladenosine (m6A) Readers
N 6-methyladenosine (m6A) is the most abundant post-transcriptional modification in mRNA,
and regulates critical biological functions via m6A reader proteins that bind to m6A …
and regulates critical biological functions via m6A reader proteins that bind to m6A …
Functions of RNA N6-methyladenosine modification in cancer progression
B Chen, Y Li, R Song, C Xue, F Xu - Molecular Biology Reports, 2019 - Springer
Abstract N6-methyladenosine (m6A) serves as a major RNA methylation modification and
impacts the initiation and progression of various human cancers through diverse …
impacts the initiation and progression of various human cancers through diverse …
Genome-wide identification of m6A-associated single-nucleotide polymorphisms in Parkinson's disease
X Qiu, H He, Y Huang, J Wang, Y Xiao - Neuroscience Letters, 2020 - Elsevier
Abstract N 6-methyladenosine (m 6 A)-associated single nucleotide polymorphisms (SNPs)
play a vital role in several neurological diseases. However, little is known about the …
play a vital role in several neurological diseases. However, little is known about the …
[HTML][HTML] Epitranscriptomics of cardiovascular diseases
S Leptidis, E Papakonstantinou… - International …, 2022 - spandidos-publications.com
RNA modifications have recently become the focus of attention due to their extensive
regulatory effects in a vast array of cellular networks and signaling pathways. Just as …
regulatory effects in a vast array of cellular networks and signaling pathways. Just as …