Abstract The Epstein-Barr virus (EBV) has been linked to the development of a variety of
human malignancies, including Burkitt's lymphoma, Hodgkin's disease, nasopharyngeal …

In 1982 Stein and coworkers identified a new molecule, CD30 (Ki-1), which is expressed by
Reed–Sternberg (RS) cells of Hodgkin's Disease (HD)(1). Although CD30 is not a specific …

Epstein-Barr virus (EBV) genome-positive nasopharyngeal carcinomas (NPCs) regularly
express the virus-coded nuclear antigen EBNA1, but not other EBNAs, and a subset of …

MicroRNAs (miRNAs) have been implicated in sequence-specific cleavage, translational
repression or deadenylation of specific target mRNAs resulting in post-transcriptional gene …

Previous studies on Epstein-Barr virus (EBV)-positive B-cell lines have identified two distinct
forms of virus latency. Lymphoblastoid cell lines generated by virus-induced transformation …

Epstein-Barr virus (EBV) is associated with a number of different human tumors and appears
to play different pathogenetic roles in each case. Thus, immunoblastic B cell lymphomas of …

Epstein-Barr virus nuclear antigen 2 (EBNA 2) activates transcription of specific genes and is
essential for B-lymphocyte transformation. EBNA 2 has an acidic activation domain which …

Epstein–Barr virus (EBV) is etiologically linked to endemic Burkitt lymphoma (BL), but its
contribution to lymphomagenesis, versus that of the chromosomal translocation leading to c …

Infection of primary B‐lymphocytes by Epstein‐Barr virus (EBV) leads to growth
transformation of these B‐cells in vitro. EBV nuclear antigen 2 (EBNA2), one of the first …

Upon infection of human B lymphocytes, the 172-kbp Epstein-Barr virus genome forms a
covalently closed circle via its terminal repeats. This event brings all of the promoters that …